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首页> 外文期刊>Gynecological endocrinology: the official journal of the International Society of Gynecological Endocrinology >Follicle-stimulating hormone associates with metabolic factors in postmenopausal women
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Follicle-stimulating hormone associates with metabolic factors in postmenopausal women

机译：卵泡刺激激素与绝经后妇女的代谢因子相关联

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摘要

Current studies have focused more on the relationships among estrogen, androgen, and metabolic syndrome (MetS). The main aim of the study was to investigate whether the variation of FSH is associated with metabolic factors in postmenopausal women. A total of 561 postmenopausal women aged 39-69 years were selected. FSH, estradiol, fasting blood glucose, and lipid profiles were analyzed. Compared with women in the highest FSH quartile, women in the lowest quartile had higher body mass index (BMI), fast blood glucose (FBG), triglyceride (TG), blood pressure, and serum estradiol (E-2) but lower high-density lipoprotein (HDL) (all p .05). Compared with women in the groups of normal levels of MetS biomarkers, women in the abnormal groups had lower FSH (all p .01). Increased quartiles of FSH were associated with significantly decreased rates of abnormal levels of metabolic factors (all p .05). High FSH levels had protective effects regarding SBP, DBP, and FBG, with odds ratios (ORs) of 0.84 (95% CI 0.76-0.92, p .001), 0.85 (95% CI 0.78-0.94, p .01), 0.90 (95% CI 0.83-0.98, p .01), respectively. Low FSH appears to be a risk factor of all domains of MetS in postmenopausal women, which merits further study.
机译：目前的研究更加专注于雌激素，雄激素和代谢综合征（Mets）之间的关系。该研究的主要目的是探讨FSH的变异是否与绝经后妇女的代谢因子有关。共选出39-69岁的561名绝经后妇女。分析FSH，雌二醇，空腹血糖和脂质型材。与最高的妇女在最高的四分位数相比，最低四分位数的女性具有更高的体重指数（BMI），快速血糖（FBG），甘油三酯（Tg），血压和血清雌二醇（E-2），但下降 - 密度脂蛋白（HDL）（所有P <.05）。与女性在正常水平的Mets Biomarkers中相比，异常组中的女性具有较低的FSH（所有P <.01）。增加的FSH四分位数与代谢因子的异常水平的显着降低有关（所有P <.05）。高FSH水平具有关于SBP，DBP和FBG的保护作用，具有0.84（95％CI 0.76-0.92，P＆LT; 0.01），0.85（95％CI 0.78-0.94，P＆。 01），0.90（95％CI 0.83-0.98，P <.01）。低FSH似乎是绝经后妇女所有Mets领域的危险因素，其优异的进一步研究。

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