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首页> 外文期刊>Gynecological endocrinology: the official journal of the International Society of Gynecological Endocrinology >Breast metastasis two years after pelvic surgery and adjuvant chemotherapy for serous ovarian cancer
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Breast metastasis two years after pelvic surgery and adjuvant chemotherapy for serous ovarian cancer

机译：骨盆手术两年后乳腺转移和静态卵巢癌的辅助化疗

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摘要

Ovarian cancer is considered the leading cause of death among gynecologic neoplasias. Breast metastases from primary ovarian cancer have been reported in only 0.03-0.6% of all breast cancers. A 38-year-old female, multipara, affected by advanced ovarian cancer and undergone a total abdominal hysterectomy with bilateral salpingo-oophorectomy, omentectomy, and pelvic peritonectomy two years earlier, was discovered to have a breast metastasis. She underwent a quadrantectomy (QSI) with an open biopsy of nodularity attached to the pectoral muscle fascia: on definitive histological characterization the breast lesions showed a high-grade invasive carcinoma, with papillary serum differentiation, and the immunohistochem-istry study of breast lesion showed positivity for cytokeratin 7 and an extensive positivity for Wilm's tumor (WT)-1 and paired box 8 (PAX8). These aspects are indicative of mammary metastasis from carcinoma of ovarian origin. Despite their rarity, metastases to breast from ovarian cancer should be considered possible because their recognition and differentiation compared to primary tumors are crucial for prognosis. Future clinical studies on MOCB should be performed to discover new specific markers for a more accurate histopathological diagnosis and to establish the real need of surgical treatment.
机译：卵巢癌被认为是妇科肿瘤中死亡的主要原因。原发性卵巢癌的乳腺转移仅在所有乳腺癌的0.03-0.6％中报道。发现受晚期卵巢癌的38岁的女性多马拉，并经过两年前与双侧泻卵体切除术，易切除术和骨盆腹膜切除术的总腹部子宫切除术治疗，有乳房转移。她接受了四阵容（QSI），伴随着胸肌筋膜的开放活检：关于胸肌筋膜的结节性：关于乳腺血清分化的乳腺病变表明乳腺病变的高级侵袭性癌，以及对乳腺病变的免疫组织研究表明细胞角蛋白7的阳性和威尔莫肿瘤（WT）-1和配对盒8的广泛阳性（PAX8）。这些方面表明卵巢血管癌的乳腺转移。尽管他们罕见地，患有卵巢癌的乳腺转移应该被认为是可能的，因为与原发性肿瘤相比的识别和分化是至关重要的，对于预后至关重要。应进行未来对MOCB的临床研究，以发现更准确的组织病理学诊断，并建立外科治疗的真实需要。

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