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首页> 外文期刊>Gynecological endocrinology: the official journal of the International Society of Gynecological Endocrinology >Assessment of thyroid functions and thyroid volume in normal pregnant Egyptian females
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Assessment of thyroid functions and thyroid volume in normal pregnant Egyptian females

机译：甲状腺功能和甲状腺卷中常规怀孕埃及女性的评估

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The normal range of thyroid functions during pregnancy differs between ethnic groups. This study assessed the thyroid functions in normal pregnant Egyptian females. Thyroid peroxidase antibodies (TPO Abs) and thyroid volume were also assessed. The study included 150 normal pregnant Egyptian females, recruited from Cairo University Hospital Antenatal Care Clinic (50 in each trimester), with 40 age-matched non-pregnant females, as a control group. Serum thyroid stimulating hormone (TSH) and TPO Abs were measured. Thyroid volume was assessed by ultrasonography. TSH ranges were 0.21-1.7, 0.52-3.2 and 0.72-2.6 mIU/L during first, second and third trimesters, respectively. The mean TSH level in pregnant females was significantly lower than that of non-pregnant women (1.2 +/- 0.7 vs 2.7 +/- 0.9 mIU/L, p < .001). TPO Abs were significantly higher in the first trimester compared to both second and third trimesters (p < .001 for both). Thyroid volume of pregnant females was non-significantly higher than that of non-pregnant control subjects (p = .126). A significant positive correlation was found between thyroid volume and body mass index in pregnant females (p < 0.001). Our study established trimester-specific reference ranges for thyroid functions in normal pregnant Egyptian females. A larger population-based study would help to confirm those ranges. Thyroid volume was non-significantly higher than that of non-pregnant control subjects.
机译：妊娠期间甲状腺功能的正常范围不同于族裔群体。该研究评估了正常怀孕埃及女性的甲状腺功能。还评估了甲状腺过氧化物酶抗体（TPO ABS）和甲状腺体积。该研究包括150名正常怀孕的埃及女性，从开罗大学医院产前医疗诊所（每个三月50岁）招募，其中40岁的非怀孕女性，作为对照组。测量血清甲状腺刺激激素（TSH）和TPO ABS。通过超声检查评估甲状腺体积。 TSH范围分别为0.21-1.7,0.52-3.2和0.72-2.6 miu / l，分别在第一，第二和第三个三个月。怀孕女性的平均TSH水平显着低于非孕妇（1.2 +/- 0.7 Vs 2.7 +/- 0.9 miU / L，P <.001）。与第二个和第三个三个三个月和第三个三个月相比，TPO ABS显着更高（两者都有P <.001）。怀孕女性的甲状腺体积不显着高于非孕妇对照受试者（P = .126）。在怀孕女性中的甲状腺体积和体重指数之间发现了显着的阳性相关性（P <0.001）。我们的研究成立了妊娠期埃及女性的甲状腺功能的三个特异性参考范围。基于人口的更大的研究将有助于确认这些范围。甲状腺体积非显着高于非孕妇对照受试者。

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