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Menstrual cycle-related fluctuations in oxytocin concentrations: A systematic review and meta-analysis

机译:催产素浓度的月经周期相关波动:系统审查和荟萃分析

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摘要

Oxytocin affects physiological and psychological functions that are often expressed sex-specifically, suggesting interactions between oxytocin and sex hormones. As female sex hormone concentrations change during the menstrual cycle, oxytocin might fluctuate, too. This systematic review and meta-analysis investigated endogenous oxytocin concentrations across menstrual cycle phases in healthy women. Data from 13 studies (120 women) showed a significant increase of oxytocin concentrations from the early follicular phase to ovulation (g = 0.39 [0.25; 0.53], p .001) and a significant decrease from ovulation to the mid-luteal phase (g = -0.50 [-0.81; -0.18], p .001). There were no significant differences between the early follicular and mid-luteal phase (g = -0.19 [-0.70; -0.32], p =.471). These findings contribute to a deeper understanding of differences in normal and abnormal psychobiological processes in women. They highlight the necessity to consider the menstrual cycle phase in studies on oxytocin in women.
机译:催产素影响通常表达性别的生理和心理功能 - 特别是催产素和性激素之间的相互作用。随着女性性激素浓度在月经周期期间发生变化,催产素也可能波动。这种系统评价和荟萃分析研究了健康女性中经期循环阶段的内源性催产素浓度。来自13项研究(120名女性)的数据表现出从早期卵泡相到排卵的催产素浓度的显着增加(G = 0.39 [0.53],P& .001),并且从排卵中显着降低到中生阶段(g = -0.50 [-0.81; -0.18],p& .001)。早期卵泡和中叶相之间没有显着差异(G = -0.19 [-0.70; -0.32],p = .471)。这些发现有助于更深入地了解女性正常和异常心理学过程的差异。它们突出了需要考虑妇女催产素研究中的月经周期阶段的必要性。

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