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The dextrans as vehicles for gene and drug delivery

机译:葡聚糖作为基因和药物递送的车辆

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摘要

Dextran has become a hot research topic in drug vehicle material because of its biodegradable, nonspecific cell adhesion, resistance to protein adsorption, low price and ease of structural modification. The fate and changes of dextran in vivo are not fully understood. It is helpful to guide the design and modification of dextran drug vehicles to clarify the changes in the morphology, metabolism and function of drug targets. With the deep understanding of dextran and the emergence of new functional dextran derivatives, its application in nanodrug delivery systems will be more and more, clinically applicable delivery systems may also be available.
机译:葡聚糖已成为药物车辆材料中的热门研究课题,因为其可生物降解,非特异性细胞粘附,抗蛋白质吸附,低价格和结构改性的易容易性。 Vivo中葡聚糖的命运和变化尚未完全理解。 引导葡聚糖毒品车辆的设计和修改是有帮助的,以阐明药物靶标的形态,代谢和功能的变化。 随着对葡聚糖的深入理解和新功能葡聚糖衍生物的出现,其在纳米凹输送系统中的应用将越来越多,临床上适用的递送系统也可以使用。

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