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SHOULD MOLECULAR TECHNOLOGY REPLACE URINE CYTOLOGY?

机译:分子技术应该替代尿液细胞学吗?

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摘要

Patients presenting with haematuria continue to form a significant proportion of the workload of urological departments. It is known that >26% of patients will have a significant pathological cause for their haematuria . Urine cytology is amongst the many investigations used; in some centres it is used as 'primary screening1 whilst in others it is used as a last attempt at reassurance that no malignant or premalignant condition exists. In other centres it has been abandoned. Nonetheless its use continues despite its variable sensitivity and specificity. For superficial disease, urine cytology has a sensitivity and specificity of 21% and 99%, respectively . In addition, it involves the transport of specimens to laboratories, specimen preparation and laboratory personnel time, and analysis and reporting time, as well as secretarial time
机译:出现血尿的患者继续占泌尿科工作量的很大一部分。众所周知,> 26%的患者会有血尿的严重病理原因。尿液细胞学是众多研究中的一项。在某些中心,它被用作“初次筛查”,而在另一些中心,它被用作确保没有恶变或恶变前病症的最后尝试。在其他中心,它已被废弃。尽管如此,尽管它具有可变的敏感性和特异性,但仍继续使用。对于浅表疾病,尿液细胞学检查的敏感性和特异性分别为21%和99%。此外,它涉及将标本运送到实验室,标本制备和实验室人员的时间,分析和报告时间以及秘书时间。

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