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首页> 外文期刊>BJU international >Do urological symptoms cluster among women? Results from the Boston Area Community Health Survey.
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Do urological symptoms cluster among women? Results from the Boston Area Community Health Survey.

机译:泌尿系统症状会在女性中聚集吗?波士顿地区社区健康调查的结果。

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摘要

OBJECTIVES: To conduct a cluster analysis of urological symptoms among women in the Boston Area Community Health (BACH) Survey, to describe the distribution of urological symptoms within each cluster, and to determine whether comorbidities, demographic characteristics, and lifestyle factors were associated with cluster membership. SUBJECTS AND METHODS: The BACH Survey is a racially and ethnically diverse random sample (3205 women) of community-dwelling residents of Boston, MA, USA, aged 30-79 years. Fourteen urological symptoms measured by participant self-report (using previously validated scales) were included in this analysis. Cluster analyses were conducted using hierarchical and non-hierarchical (k-means) methods. Within clusters, demographic characteristics, risk factors for urological symptoms and the interference of symptoms with daily activities were also assessed. RESULTS: Three-quarters of the sample reported at least one urological symptom; four symptom clusters were identified. Most symptomatic women (54%) were assigned to Cluster 1, which was characterized by storage symptoms (nocturia and urinary frequency) with an accompanying low prevalence of other urological symptoms; a second cluster was distinguished by frequency symptoms. Clusters 3 and 4 were characterized by a high prevalence of urinary incontinence and had increased interference scores and more symptoms overall (including voiding and post-voiding symptoms) than the other two clusters. Cluster 4 (8% of symptomatic women) was characterized by a high prevalence of nearly all urological symptoms and the highest interference score. In this most symptomatic cluster, body size and waist circumference were markedly higher, as was the prevalence of diabetes, hypertension and cardiovascular disease than in the other cluster groups or asymptomatic women. Women in Cluster 4 were more likely to be surgically menopausal, or to have had other forms of urogynaecological surgeries than women in the other clusters. CONCLUSION: Four distinct clusters of urological symptoms were identified among symptomatic women in the BACH Survey, two of which had a high prevalence of urinary incontinence. These cluster patterns provide a novel, empirically-based framework for investigating aetiological mechanisms and management outcomes for common urological symptoms in women.
机译:目的:在波士顿地区社区健康(BACH)调查中对女性泌尿系统症状进行聚类分析,以描述每个聚类中泌尿系统症状的分布,并确定合并症,人口统计学特征和生活方式因素是否与聚类相关成员资格。受试者与方法:BACH调查是美国马萨诸塞州波士顿市30-79岁社区居民的种族和种族随机抽样(3205名女性)。通过参与者自我报告(使用先前验证的量表)测量的十四种泌尿系统症状包括在该分析中。使用层次和非层次(k均值)方法进行聚类分析。在集群中,还评估了人口统计学特征,泌尿科症状的危险因素以及症状对日常活动的干扰。结果:四分之三的样本至少报告了一种泌尿系统症状;确定了四个症状群。大多数有症状的妇女(54%)被分配到第1组,其特点是有贮藏症状(夜尿和尿频),伴随着其他泌尿科症状的低发。第二类通过频率症状来区分。第3组和第4组的特征是尿失禁的患病率高,并且干扰评分更高,并且总体上比其他两个组具有更多的症状(包括排尿和排尿后症状)。第4组(占有症状女性的8%)的特征是几乎所有泌尿科症状患病率高,干扰评分最高。在这个最有症状的人群中,与其他人群或无症状女性相比,体形和腰围明显更高,糖尿病,高血压和心血管疾病的患病率也更高。第4组中的女性比其他组中的女性更容易手术绝经,或进行其他形式的泌尿妇科手术。结论:在BACH调查中,有症状女性中有四个明显的泌尿系统症状群,其中两个尿失禁患病率较高。这些分类模式提供了一个新颖的,基于经验的框架,用于调查妇女常见泌尿系统症状的病因机制和治疗结果。

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