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首页> 外文期刊>Maternal & child nutrition >The effect of subclinical infantile thiamine deficiency on motor function in preschool children
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The effect of subclinical infantile thiamine deficiency on motor function in preschool children

机译：亚临床幼儿硫胺素缺陷对学龄前儿童运动功能的影响

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Abstract We investigated the long‐term implications of infantile thiamine (vitamin B1) deficiency on motor function in preschoolers who had been fed during the first 2?years of life with a faulty milk substitute. In this retrospective cohort study, 39 children aged 5–6?years who had been exposed to a thiamine‐deficient formula during infancy were compared with 30 age‐matched healthy children with unremarkable infant nutritional history. The motor function of the participants was evaluated with The Movement Assessment Battery for Children (M‐ABC) and the Zuk Assessment. Both evaluation tools revealed statistically significant differences between the exposed and unexposed groups for gross and fine motor development ( p ??.001, ball skills p ?=?.01) and grapho‐motor development ( p ?=?.004). The differences were especially noteworthy on M‐ABC testing for balance control functioning ( p ??.001, OR 5.4; 95% CI 3.4–7.4) and fine motor skills ( p ??.001, OR 3.2; 95% CI 1.8–4.6). In the exposed group, both assessments concurred on the high rate of children exhibiting motor function difficulties in comparison to unexposed group (M‐ABC: 56% vs. 10%, Zuk Assessment: 59% vs. 3%, p ??.001). Thiamine deficiency in infancy has long‐term implications on gross and fine motor function and balance skills in childhood, thiamine having a crucial role in normal motor development. The study emphasizes the importance of proper infant feeding and regulatory control of breast milk substitutes.
机译：摘要我们调查了婴儿硫胺素（维生素B1）缺乏对在前两年的喂养期间喂养的学龄前儿童的运动功能的长期影响。在这个回顾性队列研究中，39名5-6岁的儿童（5-6岁以下儿童）与30岁以下的患者在婴儿期间暴露于硫胺素缺乏公式，与30名患有不起眼的婴儿营养历史的30岁匹配的健康儿童进行了比较。参与者的电机功能被儿童运动评估电池（M-ABC）和ZUK评估评估。两个评估工具都揭示了暴露和未曝光的总体和精细电机开发的暴露和未曝光群体之间的统计学意义（p？001，球技能p？=Δs.01）和Grapho-Motor开发（P？= 004） 。对平衡控制功能的M-ABC测试差异尤其值得注意（P？001，或5.4; 95％CI 3.4-7.4）和精细电机技能（P？001，或3.2; 95 ％ci 1.8-4.6）。在暴露的群体中，与未苏曝光组相比，在表现出电机功能困难的儿童高速率的两项评估（M-ABC：56％，Zuk评估：59％vs.3％，p？< .001）。婴儿期的硫胺素缺乏对童年的毛重和精细电机功能和平衡技能的长期影响，硫胺素在正常运动发展中具有至关重要的作用。该研究强调了适当婴儿喂养和对母乳替代品监管控制的重要性。

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