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Relationship between the dietary intake, serum, and breast milk concentrations of vitamin A and vitamin E in a cohort of women over the course of lactation

机译:在哺乳期妇女队列中维生素A和维生素E与维生素A和维生素E之间的关系

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Abstract This study evaluated the nutritional status of lactating women with regard to vitamins A and E and the relationship between dietary intake and concentrations in serum and milk. A longitudinal study was conducted with 43 women at a hospital in northeastern Brazil. Blood and milk samples and food intake recalls were obtained at three moments during the breastfeeding period. Retinol and alpha‐tocopherol were analysed by high‐performance liquid chromatography. Dietary inadequacy was analysed according to the estimated average requirement, with intrapersonal variation adjusted by the multiple source method. Food intake was classified by quartiles of consumption. Serum retinol was 1.65?μmol/L, with 5% of low concentrations (0.7?μmol/L) at the first collection. Serum alpha‐tocopherol decreased from 30.18 to 25.49?μmol/L at the third collection ( P ?=?0.008), with an increase in the percentage frequency of deficiency (12?μmol/L). Both vitamins maintained stable concentrations in milk at the different collection times, and the overall dietary inadequacy of vitamins A and E was 58% and 100%, respectively. There was a correlation only between vitamin A intake and serum retinol ( r ?=?0.403, P ?=?0.007), and higher retinol concentrations were found in women classified in the highest consumption quartile ( P ?=?0.031). Over the course of lactation, there was a high degree of inadequacy in vitamin intake and a reduction in serum alpha‐tocopherol, whereas its concentrations in milk remained unchanged. Dietary intake of vitamin A has been shown to influence serum retinol, which underscores the importance of adequate nutrition and monitoring of vitamin deficiency during lactation.
机译:摘要本研究评估了哺乳期A和E的哺乳期妇女的营养状况以及血清和牛奶中膳食摄入和浓度之间的关系。在巴西东北部的医院进行了43名女性进行了纵向研究。在母乳喂养期间在三个时刻获得血液和牛奶样品和食物进气量召回。通过高效液相色谱法分析视黄醇和α-生育酚。根据估计的平均要求分析膳食不足,通过多种源法调节的内部变化。食物摄入量被四分位于消费量分类。血清视黄醇是1.65Ωμmol/ L,在第一个收集时具有5%的低浓度(& 0.7μmol/ l)。血清α-生育酚从第三集(P?= 0.008)的30.18〜25.49?μmol/ l减少(p?= 0.008),缺乏百分比率(<12?μmol/ L)。两种维生素在不同的收集时间内保持牛奶中的稳定浓度,维生素A和E的整体膳食不足分别为58%和100%。仅在维生素A摄入量和血清视黄醇之间存在相关性(R?= 0.403,p?= 0.007),并且在分类为最高消费四分位数的女性中发现了更高的视黄醇浓度(p?= 0.031)。在泌乳过程中,维生素摄入量高度不足,血清α-生育酚的减少,而其在牛奶中的浓度保持不变。已经显示维生素A的膳食摄入量影响血清视黄醇,这抑制了哺乳期间足够营养和对维生素缺乏监测的重要性。

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