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首页> 外文期刊>Medicine and science in sports and exercise >The Impact of Morning versus Afternoon Exercise on Iron Absorption in Athletes
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The Impact of Morning versus Afternoon Exercise on Iron Absorption in Athletes

机译:早上与下午运动对运动员的铁吸收的影响

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Purpose This study examined postexercise inflammatory, hepcidin, and iron absorption responses to endurance exercise performed in the morning versus the afternoon. Methods Sixteen endurance-trained runners (10 male, 6 female) with serum ferritin (sFer) < 50 mu g center dot L-1 completed a 90-min running protocol (65% vVO(2max)) in the morning (am), or the afternoon (pm), in a crossover design. An iron-fortified fluid labeled with stable iron isotopes (Fe-57 or Fe-58) was administered with a standardized meal 30 min following the exercise and control conditions during each trial, serving as a breakfast and dinner meal. Venous blood samples were collected before, immediately after, and 3 h after the exercise and control conditions to measure sFer, serum interleukin-6 (IL-6), and serum hepcidin-25. A final venous blood sample was collected 14 d after each trial to determine the erythrocyte iron incorporation, which was used to calculate iron absorption. Linear mixed-modeling was used to analyze the data. Results Overall, exercise significantly increased the concentrations of IL-6 (4.938 pg center dot mL(-1); P = 0.006), and hepcidin-25 concentrations significantly increased 3 h after exercise by 0.380 nM (P < 0.001). During the pm trial, hepcidin concentrations exhibited diurnal tendency, increasing 0.55 nM at rest (P = 0.007), before further increasing 0.68 nM (P < 0.001) from prerun to 3 h postrun. Fractional iron absorption was significantly greater at breakfast after the am run, compared with both the rested condition (0.778%; P = 0.020) and dinner in the am run trial (0.672%; P = 0.011). Conclusions Although exercise resulted in increased concentrations of IL-6 and hepcidin, iron was best absorbed in the morning after exercise, indicating there may be a transient mechanism during the acute postexercise window to promote iron absorption opposing the homeostatic regulation by serum hepcidin elevations.
机译:目的本研究检查了炎症,肝素和铁的耐血液锻炼和下午进行的耐力运动。方法使用血清铁蛋白(SFER)<50 mu G中心点L-1的16次耐久训练赛跑者(10只雄性,6个雌性)完成了90分钟的运行方案(65%VVO(2max)),或者下午(PM),在交叉设计中。在每次试验期间的运动和控制条件下,用标准化的膳食施用标有稳定的铁同位素(Fe-57或Fe-58)的铁强化液,在每次试验期间的运动和控制条件下,用作早餐和晚餐。在运动和控制条件下,在运动和控制条件下,以后,在3小时以后收集静脉血样,以测量SFER,血清白细胞介素-6(IL-6)和血清肝素-25。每次试验后收集最终静脉血液样品14d,以确定用于计算铁吸收的红细胞铁掺入。线性混合建模用于分析数据。结果总体而言,运动显着增加了IL-6的浓度(4.938Pg中心点M1(-1); p = 0.006),运动后肝素-25浓度显着增加3小时,运动速度为0.380nm(p <0.001)。在PM试验期间,Hepcidin浓度表现出昼夜倾向,静置时增加0.55nm(p = 0.007),然后从Prerun进一步增加0.68nm(p <0.001),从prerun到3 h postrun。早餐后,在AM运行后,早餐在早餐时,分数较大,与恢复条件(0.778%; p = 0.020)和AM运行试验中的晚餐(0.672%; P = 0.011)。结论虽然运动导致IL-6和肝素的浓度增加,但锻炼后的早晨最佳地被吸收,表明在急性切除窗口期间可能存在瞬态机制,以促进血清肝素升高的稳压调节的铁吸收。

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