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首页> 外文期刊>Medycyna Weterynaryjna >Clinical efficacy of marbofloxacin in dogs and cats diagnosed with lower urinary tract disorders
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Clinical efficacy of marbofloxacin in dogs and cats diagnosed with lower urinary tract disorders

机译：患有低尿路疾病诊断的犬毒素和猫的临床疗效

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Marbofloxacin is one of the fluoroquinolones developed exclusively for veterinary medicine. The primary aim of the present study is to identify and assess evidence for marbofloxacin's clinical efficacy in the treatment of urinary tract infections in small animal practice. The study included 118 dogs and 123 cats that were referred to the Internal Medicine Department with lower urinary tract symptoms. We excluded animals that had received antimicrobial or anti-inflammatory therapy in the previous 15 days. Diagnosis was confirmed by clinical findings, urinalysis, and imaging. Rectal temperature, appetite, urinary signs, and abdominal pain were monitored during two visits (day 0 and 14). The timetable depended on the diagnosis of the following: two urinalyses, two bacterial examinations, and antibacterial susceptibility testing were performed for each case. Bacterial UTI were confirmed in 36 dogs and 28 cats. Urine samples were collected on day 0, which demonstrated the presence of various bacteria, with a marked predominance of P. mirabilis and coagulase-positive Staphylococci in canine and feline urine samples, respectively. Antimicrobial susceptibility test results revealed 25 (65.7%) of dog isolates and 24 (85.7%) of cat isolates were susceptible to marbofloxacin. Treatment of UTIs is generally challenging for the small animal practitioner. Because of the need for long-term antimicrobials, bacterial culture and susceptibility tests are especially important for successful treatment. Marbofloxacin can be part of an effective treatment of UTIs in dogs and cats.
机译：马巴诺氧氟沙林是一种专门用于兽医药物的氟喹啉。本研究的主要目的是识别并评估马巴福氧氟沙星在小动物实践中治疗泌尿道感染时的临床疗效的依据。该研究包括118只狗和123只猫，称为内科患者，尿路症状较低。我们排除了在过去15天内接受抗菌或抗炎治疗的动物。通过临床发现，尿症和成像证实了诊断。在两次访问期间监测直肠温度，食欲，尿征和腹痛（第0天和第14天）。该时间表取决于以下诊断：对每种情况进行两种局部尿素，两种细菌检查和抗菌敏感性测试。细菌UTI在36只狗和28只猫。在第0天收集尿液样本，其展示了各种细菌的存在，分别具有犬和猫哺乳动物样品的P. mirabilis和凝血酶阳性葡萄球菌的显着优势。抗微生物易感性测试结果显示25（65.7％）犬分离物，24个（85.7％）的猫分离物易患马巴氟沙星。对小动物从业者的治疗通常挑战。由于需要长期抗微生物剂，细菌培养和易感性测试对于成功治疗尤为重要。马巴诺氧氟辛可以是有效治疗狗和猫的有效治疗的一部分。

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