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首页> 外文期刊>Mikrochimica Acta: An International Journal for Physical and Chemical Methods of Analysis >Simultaneous voltammetric determination of acetaminophen, naproxen, and theophylline using an in-situ polymerized poly(acrylic acid) nanogel covalently grafted onto a carbon black/La2O3 composite
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Simultaneous voltammetric determination of acetaminophen, naproxen, and theophylline using an in-situ polymerized poly(acrylic acid) nanogel covalently grafted onto a carbon black/La2O3 composite

机译:使用原位聚合的聚(丙烯酸)纳米凝胶在炭黑/ La2O3复合材料上的原位聚合的聚(丙烯酸)纳米凝胶同时伏安致乙酰氨基酚,萘普生和茶碱的致乙酰氨基酚和茶碱

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摘要

Lanthanum oxide nanomaterials were decorated with carbon black (CB) and grafted with a poly(acrylic acid) nanogel to obtain a composite material (CB-g-PAA/La2O3) for simultaneous determination of acetaminophen (AMP), naproxen (NPX), and theophylline (TPH). The nanogel was synthesized by in-situ free radical polymerization. The composite was dropped onto a glassy carbon electrode (GCE), and the modified GCE displays robust electrocatalytic activity towards AMP, NPX, and TPH, with voltammetric signals that are enhanced compared to a bare GCE. Features of merit for AMP, NPX, and TPH, respectively, include (a) peak potentials of 0.42, 0.85 and 0.12 V (vs. Ag/AgCl), (b) linear ranges from 0.05-887, 0.05-884, and 0.02-888 mu M, and (c) detection limits of 20, 35, and 15 nM. The practical applicability of the CB-g-PAA/La2O3/GCE was illustrated by analyzing serum and urine samples.
机译:氧化镧纳米材料用炭黑(Cb)装饰,并用聚(丙烯酸)纳米凝胶接枝,得到复合材料(CB-G-PAA / La2O3),用于同时测定乙酰氨基酚(AMP),萘普生(NPX)和 茶碱(TPH)。 通过原位自由基聚合合成纳米粒子。 将复合材料滴到玻璃状碳电极(GCE)上,并且改性的GCE显示朝向AMP,NPX和TPH的鲁棒电催化活性,与裸GCE相比,伏安信号增强。 AMP,NPX和TPH的优点的特征,包括(a)0.42,0.85和0.12 V(与Ag / AgCl),(B)线性范围为0.05-887,0.05-884和0.02的峰电位 -888 mu m,(c)检测限为20,35和15nm。 通过分析血清和尿液样品来说明CB-G-PAA / LA2O3 / GCE的实际适用性。

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