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Evidence of HIV epidemics among non-injecting drug users in Iran: A systematic review

机译:伊朗非注射吸毒者中艾滋病毒流行的证据:系统回顾

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Aims: In Iran, injecting drug users have been recognized as a high-risk group for HIV/AIDS for years. However, evidence of HIV epidemics in non-injecting drug users (non-IDUs) has also been found in recent years. The aim of this systematic review was to determine the prevalence of HIV in non-IDUs in Iran. Methods: International and regional databanks, including Pubmed, ISI, CINAHL, ASCI and IMEMR, as well as domestic databanks such as IranPsych, IranMedex SID and research reports were searched, and extensive personal contacts were made. All studies with HIV testing conducted between 1998 and 2007, which included non-IDU subjects, were gathered and their qualities were assessed. HIV prevalence was pooled for each gender and stratified to several categories. The prevalence of HIV in non-IDUs and IDUs was compared using pooled odds ratios in a fixed meta-analysis model. Results: Overall, 10 studies with 2275 non-IDU samples were included. Six of the studies were conducted in prison settings, two in treatment centres, one in a community setting and one in a shelter setting. Four studies were performed in Tehran, the capital city of Iran. The pooled HIV prevalence was 5.4% [95% confidence interval (CI) 3.7-7.4] after 2005, which was significantly higher than the prevalence before 2005 [1.6% (95% CI 1.0-2.3)]. IDUs were 4.36 (95% CI 2.63-7.24) times more likely to be infected with HIV than non-IDUs. Conclusion: Iran is facing a major HIV epidemic among non-injecting illicit drug users, which necessitates an urgent preventive response.
机译:目的:在伊朗,注射吸毒者多年来一直被认为是艾滋病毒/艾滋病的高危人群。但是,近年来还发现了非注射吸毒者(非注射吸毒者)中艾滋病毒流行的证据。这项系统审查的目的是确定伊朗非注射毒品使用者中的艾滋病毒流行率。方法:检索国际和区域数据库,包括Pubmed,ISI,CINAHL,ASCI和IMEMR,以及国内数据库,例如IranPsych,IranMedex SID和研究报告,并进行广泛的个人联系。收集了1998年至2007年之间进行的所有艾滋病毒检测研究,其中包括非注射毒品者,并对其质量进行了评估。汇总了每种性别的艾滋病毒流行率,并分为几个类别。在固定的荟萃分析模型中,使用合并的比值比对非IDU和IDU中HIV的患病率进行了比较。结果:总体上,包括10项研究,其中包含2275个非药物治疗的样本。其中六项研究是在监狱环境中进行的,两项是在治疗中心进行的,一项是在社区环境中进行的,另一项是在收容所环境中进行的。在伊朗首都德黑兰进行了四项研究。 2005年之后,合并的HIV患病率为5.4%[95%置信区间(CI)3.7-7.4],大大高于2005年之前的患病率[1.6%(95%CI 1.0-2.3)]。 IDU感染艾滋病毒的可能性是非IDU的4.36倍(95%CI 2.63-7.24)倍。结论:在非注射用非法药物使用者中,伊朗正面临主要的艾滋病毒流行,因此有必要采取紧急预防措施。

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