• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Muscle and Nerve >Predicting myofiber size with electrical impedance myography: A study in immature mice
【24h】

Predicting myofiber size with electrical impedance myography: A study in immature mice

机译：用电阻抗幻想解读MyoFiber大小：在未成熟的小鼠中的研究

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

ABSTRACT Introduction : Electrical impedance can be used to estimate cellular characteristics. We sought to determine whether it could be used to approximate myofiber size using standard prediction modeling approaches. Methods : Forty‐four C57BL/6J wild‐type immature mice of varying ages underwent electrical impedance myography (EIM) with a needle electrode array placed in the gastrocnemius. Animals were then humanely killed and muscle fixed, stained, and myofiber size quantified. Two different statistical prediction models were then applied. Results : Impedance parameters showed major variation with increasing myofiber size. The prediction models based on EIM data alone were able to predict fiber size, with errors in the range of ±69.05–78.44?μm 2 (16.19%–18.40% with respect to the average myofiber size). Discussion : By using well‐established statistical models, EIM data alone can provide a satisfactory estimate of myofiber size. Additional study of this approach for approximating myofiber size without the requirement of removing tissue for histological analysis is warranted. Muscle Nerve 58 : 106–113, 2018
机译：摘要介绍：电阻抗可用于估算蜂窝特征。我们试图确定它是否可以使用标准预测建模方法来用于近似MyoFiber大小。方法：不同年龄的四十四个C57BL / 6J野生型未成熟小鼠接受电阻抗幻影（EIM），将针电极阵列放置在腓肠肌中。然后人们杀死动物和肌肉固定，染色和肌纤维尺寸量化。然后应用两个不同的统计预测模型。结果：阻抗参数显示出具有越来越多的近视尺寸的主要变化。仅基于EIM数据的预测模型能够预测光纤尺寸，误差范围为±69.05-78.44？μm2（相对于平均MyoFiber大小16.19％-18.40％）。讨论：通过使用良好的统计模型，单独的EIM数据可以提供令人满意的近视尺寸。不需要在不需要去除组织组织学分析的情况下逼近肌纤维尺寸的这种方法的另外的研究。肌神经58：106-113，2018

著录项

  • 来源
    《Muscle and Nerve》 |2018年第1期|共8页
  • 作者

    Kapur Kush; Taylor Rebecca S.; Qi Kristin; Nagy Janice A.; Li Jia; Sanchez Benjamin; Rutkove Seward B.;

  • 作者单位

    Department of NeurologyBoston Children's Hospital Harvard Medical SchoolBoston Massachusetts 02115;

    Department of NeurologyBeth Israel Deaconess Medical Center Harvard Medical School330 Brookline;

    Department of NeurologyBeth Israel Deaconess Medical Center Harvard Medical School330 Brookline;

    Department of NeurologyBeth Israel Deaconess Medical Center Harvard Medical School330 Brookline;

    Department of NeurologyBeth Israel Deaconess Medical Center Harvard Medical School330 Brookline;

    Department of NeurologyBeth Israel Deaconess Medical Center Harvard Medical School330 Brookline;

    Department of NeurologyBeth Israel Deaconess Medical Center Harvard Medical School330 Brookline;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 人体生理学;
  • 关键词

    electrical impedance myography; mouse; phase; myofiber; prediction; reactance; resistance;

    机译：电阻抗幻图;鼠标;阶段;肌电纤维;预测;电抗;阻力;

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号