Synaptic plasticity: Neuroligin 1 does the splits.

Leonie Welberg

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Synaptic plasticity: Neuroligin 1 does the splits.

机译：突触可塑性：神经源素1的分裂。

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Neuroligins are postsynaptic adhesion proteins that are essential for synaptic function, but little is known about their precise role and regulation. Neuroligin 1 (NLGN1) is located postsynaptically at gluta-matergic synapses, where it binds to the presynaptic adhesion protein neurexin 1(3 (NRX1(3). Now, two new papers shed light on the function and regulation of NLGN1. Suzuki et al. detected several NLGN1 polypeptide fragments in immunoblots of rat brains and mouse primary cortical neuronal cultures, which suggests that NLGN1 undergoes proteolytic processing.

机译：神经阳苷是对突触函数至关重要的后突触粘附蛋白，但关于其精确的作用和调节，毫无疑问。神经源蛋白1（NLGN1）在谷谷物体突触处突出，其中它与突触前粘附蛋白Neurexin 1（3（NRX1（3）。现在，两个新的纸张揭示了NLGN1的功能和调节。Suzuki等人。在大鼠大脑和小鼠初级皮质神经元培养物中检测到几种NLGN1多肽片段中，表明NLGN1经历蛋白水解加工。

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《Nature reviews neuroscience》 |2012年第12期|共1页
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Leonie Welberg;
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1. Synaptic plasticity: Neuroligin 1 does the splits. [J] . Leonie Welberg Nature reviews neuroscience . 2012,第12期

机译：突触可塑性：Neuroligin 1进行分裂。
2. Synaptic Plasticity and Excitation-Inhibition Balance in the Dentate Gyrus: Insights from In Vivo Recordings in Neuroligin-1, Neuroligin-2, and Collybistin Knockouts [J] . Peter Jedlicka, Julia Muellerleile, Stephan W. Schwarzacher Journal of Neural Transplantation and Plasticity: Neural Plasticity . 2018,第specialaissuea1apartaA期

机译：齿状回的突触可塑性和兴奋抑制平衡：从Neuroligin-1，Neuroligin-2和Collybistin敲除体内记录的见解。
3. Neuroligin 1 regulates spines and synaptic plasticity via LIMK1/cofilin-mediated actin reorganization [J] . An Liu, Zikai Zhou, Rui Dang, Journal of cell biology . 2016,第4期

机译：Neuroligin 1通过LIMK1 / cofilin介导的肌动蛋白重组来调节棘突和突触可塑性
4. Excitatory post-synaptic current and synaptic plasticity of semiconducting polymer/electrolyte system [C] . F. Zeng, X J. Li, J. T. Zhang, Non-Volatile Memory Technology Symposium . 2015

机译：聚合物/电解质体系的兴奋性突触后电流和突触可塑性
5. The role of neuroligin in synaptic remodeling. [D] . Gutierrez Herrera, Rosario Carolina. 2010

机译：Neuroligin在突触重塑中的作用。
6. Synaptic Plasticity and Excitation-Inhibition Balance in the Dentate Gyrus: Insights from In Vivo Recordings in Neuroligin-1 Neuroligin-2 and Collybistin Knockouts [O] . Peter Jedlicka, Julia Muellerleile, Stephan W. Schwarzacher 2018

机译：齿状回的突触可塑性和兴奋抑制平衡：从Neuroligin-1Neuroligin-2和Collybistin敲除体内记录的见解。
7. Neuroligin 1 regulates spines and synaptic plasticity via LIMK1/cofilin-mediated actin reorganization [O] . An Liu, Zikai Zhou, Rui Dang, 2016

机译：神经源蛋白1通过利率介导的肌动蛋白重组来调节刺和突触塑性

Synaptic plasticity: Neuroligin 1 does the splits.

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