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首页> 外文期刊>Nature reviews. Endocrinology >Global aetiology and epidemiology of type 2 diabetes mellitus and its complications
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Global aetiology and epidemiology of type 2 diabetes mellitus and its complications

机译：2型糖尿病的全球性病学和流行病学及其并发症

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摘要

Globally, the number of people with diabetes mellitus has quadrupled in the past three decades, and diabetes mellitus is the ninth major cause of death. About 1 in 11 adults worldwide now have diabetes mellitus, 90% of whom have type 2 diabetes mellitus (T2DM). Asia is a major area of the rapidly emerging T2DM global epidemic, with China and India the top two epicentres. Although genetic predisposition partly determines individual susceptibility to T2DM, an unhealthy diet and a sedentary lifestyle are important drivers of the current global epidemic; early developmental factors (such as intrauterine exposures) also have a role in susceptibility to T2DM later in life. Many cases of T2DM could be prevented with lifestyle changes, including maintaining a healthy body weight, consuming a healthy diet, staying physically active, not smoking and drinking alcohol in moderation. Most patients with T2DM have at least one complication, and cardiovascular complications are the leading cause of morbidity and mortality in these patients. This Review provides an updated view of the global epidemiology of T2DM, as well as dietary, lifestyle and other risk factors for T2DM and its complications.
机译：在全球范围内，糖尿病患者的人数在过去的三十年里有四倍，糖尿病是第九次死亡原因。世界各地的11个成年人中约有1人现在患有糖尿病，其中90％有2型糖尿病（T2DM）。亚洲是迅速新兴的T2DM全球流行病的主要领域，中国和印度是两大震票。虽然遗传易感性部分决定了对T2DM的个体易感性，但不健康的饮食和久坐生活方式是当前全球流行病的重要司机;早期发育因素（如宫内曝光）也有易感性对生命后的T2DM的作用。可以防止许多T2DM的情况改变，包括维持健康的体重，消耗健康的饮食，保持身体活跃，不适合吸烟和饮酒。大多数T2DM的患者至少有一种并发症，并且心血管并发症是这些患者的发病率和死亡率的主要原因。本次审查提供了T2DM全局流行病学的更新视图，以及T2DM的膳食，生活方式和其他危险因素及其并发症。

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