Reappraising the spectrum of AKI and hepatorenal syndrome in patients with cirrhosis

Velez Juan Carlos Q.; Therapondos George; Juncos Luis A.

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Reappraising the spectrum of AKI and hepatorenal syndrome in patients with cirrhosis

机译：重新评估肝硬化患者AKI和Hepatorenal综合征的谱

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Hepatorenal syndrome type 1 (HRS-1) is a specific type of acute kidney injury (AKI) that is largely considered a functional derangement that ultimately affects renal vasculature tone. This Review describes new insights that suggest that non-haemodynamic tubulo-toxic factors, such as endotoxins and bile acids, might mediate parenchymal renal injury in patients with cirrhosis, suggesting that concurrent mechanisms might contribute to the development of AKI in patients with cirrhosis.

机译：Hepatorenal综合征1型（HRS-1）是一种特定类型的急性肾损伤（AKI），主要被认为是最终影响肾脉管的功能性紊乱。本综述描述了新的见解，表明非血液动力学微管毒性因素，如内毒素和胆汁酸，可能会介导肝硬化患者的实质肾损伤，这表明并发机制可能有助于肝硬化患者的AKI发育。

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《Nature reviews. Nephrology》 |2020年第3期|共19页
作者
Velez Juan Carlos Q.; Therapondos George; Juncos Luis A.;
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作者单位

Ochsner Clin Fdn Dept Nephrol New Orleans LA USA;

Ochsner Clin Fdn Dept Gastroenterol Hepatol New Orleans LA USA;

Univ Arkansas Med Sciences Dept Med Div Nephrol Little Rock AR USA;

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正文语种 eng
中图分类泌尿科学（泌尿生殖系疾病）;
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1. Reappraising the spectrum of AKI and hepatorenal syndrome in patients with cirrhosis (vol 85, pg 128, 2019) [J] . Velez Juan Carlos Q., Therapondos George, Juncos Luis A. Nature reviews. Nephrology . 2020,第3期

机译：重新评估肝硬化患者AKI和Hepatorenal综合征的谱（Vol 85，PG 128,2019）
2. SIMILARITY OF OUTCOMES OF AKI IN CIRRHOSIS DUE TO ACUTE TUBULAR INJURY OR HEPATORENAL SYNDROME TYPE 1 [J] . Rivera M., Velez J. Journal of investigative medicine . 2020,第2期

机译：由于急性管状损伤或Hepatorenal综合征1型引起的肝硬化结果的相似性1
3. New insight into volume overload and hepatorenal syndrome in cirrhosis, "the hepatorenal reflex hypothesis" [J] . RzouqF., AlahdabF., OlyaeeM. The American Journal of the Medical Sciences . 2014,第3期

机译：肝硬化中容量超负荷和肝肾综合征的新见解，“肝肾反射假说”
4. Hepatorenal syndrome in cirrhosis [C] . A. L. GERBES Falk Symposium . 2008

机译：肝硬化的Hepatorenal综合征
5. Pre-Endoscopic Characteristics in Patients with Cirrhosis for Distinguishing Potentially Endoscopically Intervenable Etiologies of Upper Gastrointestinal Bleeding [D] . Cortes, Pedro. 2020

机译：肝硬化患者的预端镜下特征，以区分上胃肠出血的潜在内窥镜介入病因
6. Terlipressin-Induced Peripheral Cyanosis in a Patient with Liver Cirrhosis and Hepatorenal Syndrome [O] . Chi-Wen Chiang, Yun-Ju Lin, Yaw-Bin Huang 2019

机译：特利加压素诱导的肝硬化和肝肾综合征患者的周围发yan
7. Author Correction: Reappraising the spectrum of AKI and hepatorenal syndrome in patients with cirrhosis [O] . Juan Carlos Q. Velez, George Therapondos, Luis A. Juncos 2020

机译：作者矫正：重新评估肝硬化患者的AKI和Hepatorenal综合征的谱

Reappraising the spectrum of AKI and hepatorenal syndrome in patients with cirrhosis

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