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首页> 外文期刊>Natural product research >Traditional Mediterranean plants: characterization and use of an essential oils mixture to treat Malassezia otitis externa in atopic dogs
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Traditional Mediterranean plants: characterization and use of an essential oils mixture to treat Malassezia otitis externa in atopic dogs

机译：传统的地中海植物：表征和使用精油混合物，以治疗Atopic狗的Malassezia耳炎

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摘要

Several plants extracts from Mediterranean countries are traditionally employed in skin troubles both in humans and in animals. Malassezia pachydermatis is a lipophylic yeast responsible for otitis externa and dermatitis in dogs and for cutaneous and systemic disease in humans. Five mixtures of essential oils obtained from Mediterranean plants (Citrus paradisi, Salvia sclarea, Ocimum basilicum, Rosmarinus officinalis, Citrus limon, Anthemis nobilis, Lavandula hybrida and Thymus vulgaris) provided with antifungal and/or anti-inflammatory action assayed in vitro, were tested in vivo versus M. pachydermatis to treat once daily for 2 weeks 25 atopic dogs with Malassezia otitis externa. Mixture composed by C. limon 1%, S. sclarea 0,5%, R. officinalis 1%, A. nobilis 0,5% yielded excellent results in all treated dogs. Despite of clinical resolution after all treatments the number of blastospores did not decrease. This study confirms recent findings suggesting a multifactorial alternative approach for the management of canine Malassezia otitis.
机译：来自地中海国家的几种植物传统上用于人类和动物的皮肤麻烦。 Malassezia pachydermatis是一种脂质酵母，负责犬耳炎和皮肤炎，以及人类的皮肤和全身疾病。测试了来自地中海植物（柑橘Paradisi，Salvia Sclarea，Ocimum Basilicum，Rosmarinus Officinalis，Citrus Limilis，Anthemis Nobilis，Lavandula Hybrida和胸腺炎）的五种混合物进行了测试，在体外测定的抗真菌和/或抗炎作用在体内与M. pachydermatis每天治疗2周25个与malassezia耳炎的特应性狗。由C.Imon 1％组成的混合物，S.Sclarea 0.5％，R. Officinalis 1％，A.Bobilis0.5％在所有治疗的狗中产生优异的结果。尽管术后临床分辨率术后，但胚胎孢子的数量没有减少。本研究证实了最近的研究结果表明犬类Malassezia中耳炎的管理是一种多因素替代方法。

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