...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Neurobiology of learning and memory >Losing memories during sleep after targeted memory reactivation
【24h】

Losing memories during sleep after targeted memory reactivation

机译：在有针对性的记忆重新激活之后睡眠期间失去回忆

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Targeting memories during sleep opens powerful and innovative ways to influence the mind. We used targeted memory reactivation (TMR), which to date has been shown to strengthen learned episodes, to instead induce forgetting (TMR-Forget). Participants were first trained to associate the act of forgetting with an auditory forget tone. In a second, separate, task they learned object-sound-location pairings. Shortly thereafter, some of the object sounds were played during slow wave sleep, paired with the forget tone to induce forgetting. One week later, participants demonstrated lower recall of reactivated versus non-reactivated objects and impaired recognition memory and lowered confidence for the spatial location of the reactivated objects they failed to spontaneously recall. The ability to target specific episodic memories for forgetting during sleep has implications for developing novel therapeutic techniques for psychological disorders such as PTSD and phobias.
机译：睡眠期间的定位记忆开启了强大而创新的方式来影响心灵。 我们使用了目标内存重新激活（TMR），该迄今已被证明可以加强学到的剧集，而是引起遗忘（TMR-Forge）。 参与者首次接受培训，以涉及忘记听觉忘记语气的行为。 在第二个，单独的任务中学习对象声音位置配对。 此后不久，在慢波睡眠期间播放了一些物体声音，与忘记基调配对以引起遗忘。 一周后，参与者展示了重新激活与非重新激活的物体的较低召回，并且识别存储器受损，并降低了他们未能自发地召回的重新激活对象的空间位置的置信度。 在睡眠期间忘记遗忘的特定情节记忆的能力对开发新的治疗技术为PTSD和恐惧症等心理障碍的发展。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号