Mechanisms of Noise-Induced Tinnitus: Insights from Cellular Studies

Shore Susan E.; Wu Calvin

首页> 外文期刊>Neuron >Mechanisms of Noise-Induced Tinnitus: Insights from Cellular Studies

【24h】

Mechanisms of Noise-Induced Tinnitus: Insights from Cellular Studies

机译：噪声诱导的耳鸣机制：蜂窝研究中的见解

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Tinnitus, sound perception in the absence of physical stimuli, occurs in 15% of the population and is the top-reported disability for soldiers after combat. Noise overexposure is a major factor associated with tinnitus but does not always lead to tinnitus. Furthermore, people with normal audiograms can get tinnitus. In animal models, equivalent cochlear damage occurs in animals with and without behavioral evidence of tinnitus. But cochlear-nerve-recipient neurons in the brainstem demonstrate distinct, synchronized spontaneous firing patterns only in animals that develop tinnitus, driving activity in central brain regions and ultimately giving rise to phantom perception. Examining tinnitus-specific changes in single-cell populations enables us to begin to distinguish neural changes due to tinnitus from those that are due to hearing loss.

机译：在没有身体刺激的情况下，耳鸣，在没有身体刺激的情况下发生在15％的人口中，并且是战斗后士兵的逐步残疾。噪声过度曝光是与耳鸣相关的主要因素，但并不总是导致耳鸣。此外，常规听力图的人可以获得耳鸣。在动物模型中，在具有和没有耳鸣的行为证据的动物中发生相当的耳蜗损伤。但是脑干中的耳蜗神经受体神经元仅展示了不同的动物，仅在发生耳鸣，中央脑区的驾驶活动并最终引起幻影感知的动物。检查单个细胞群体的特定耳鸣的变化使我们能够开始区分由于耳鸣而导致的神经变化来自因听力损失而导致的耳鸣。

著录项

来源
《Neuron》 |2019年第1期|共13页
作者
Shore Susan E.; Wu Calvin;
展开▼
作者单位

Univ Michigan Dept Otolaryngol Kresge Hearing Res Inst Ann Arbor MI 48109 USA;

Univ Michigan Dept Otolaryngol Kresge Hearing Res Inst Ann Arbor MI 48109 USA;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类神经病学;
关键词

相似文献

外文文献
中文文献
专利

1. Mechanisms of Noise-Induced Tinnitus: Insights from Cellular Studies [J] . Shore Susan E., Wu Calvin Neuron . 2019,第1期

机译：噪声诱导的耳鸣机制：蜂窝研究中的见解
2. Insight from Molecular, Pathological, and Immunohistochemical Studies on Cellular and Humoral Mechanisms Responsible for Vaccine-Induced Protection of Rainbow Trout against Yersinia ruckeri [J] . Sidhartha Deshmukh, Per W. Kania, Jiwan K. Chettri, Clinical and vaccine immunology: CVI . 2013,第10期

机译：从分子，病理学和免疫组织化学研究中，细胞和体液机制负责疫苗诱导的虹鳟鱼对鲁氏耶尔森氏菌的保护
3. Mechanisms underlying autoimmune synaptic encephalitis leading to disorders of memory, behavior and cognition:insights from molecular, cellular and synaptic studies [J] . Emilia H. Moscato, Ankit Jain, Xiaoyu Peng, The European Journal of Neuroscience . 2010,第2期

机译：导致自身记忆，行为和认知障碍的自身免疫性突触脑炎的潜在机制：分子，细胞和突触研究的见解
4. Confocal imaging of whole vertebrate embryos reveals novel insights into molecular and cellular mechanisms of organ development [C] . Diana M. Hadel, Bradley B. Keller, Lisa L. Sandell Optical methods in developmental biology II . 2014

机译：整个脊椎动物胚胎的共聚焦成像揭示了器官发育的分子和细胞机制的新见解
5. The interplay of anxiety, hormones and the GABAergic system in adolescent females: Insights into the cellular mechanisms underlying behavior in an animal model of anorexia nervosa. [D] . Wable, Gauri Satish. 2015

机译：青春期女性的焦虑，激素和GABA能系统之间的相互作用：洞悉神经性厌食症动物模型中行为基础的细胞机制。
6. Insight from Molecular Pathological and Immunohistochemical Studies on Cellular and Humoral Mechanisms Responsible for Vaccine-Induced Protection of Rainbow Trout against Yersinia ruckeri [O] . Sidhartha Deshmukh, Per W. Kania, Jiwan K. Chettri, 2013

机译：从分子病理学和免疫组织化学研究中细胞和体液机制负责疫苗诱导的虹鳟鱼对耶尔森氏菌的保护作用
7. Cellular and Molecular Mechanisms Underlying Vulnerability and Resilience to Noise-Induced Tinnitus. [O] . Li Shuang 2015

机译：潜在的易感性和抗噪声性耳鸣的细胞和分子机制。
8. Studies of Aural Nonlinearity and the Mechanisms of Auditory Fatigue. Part 2. Epidemiologic Methods in Noise-Induced Hearing Loss. [R] . Erdreich, J., Erdreich, L. 1982

机译：听觉非线性研究及听觉疲劳机制。第二部分噪声诱发听力损失的流行病学方法。

Mechanisms of Noise-Induced Tinnitus: Insights from Cellular Studies

摘要

著录项

相似文献

相关主题

期刊订阅