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Partially Mixed Selectivity in Human Posterior Parietal Association Cortex

机译:部分混合的人类后视性能皮质

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摘要

To clarify the organization of motor representations in posterior parietal cortex, we test how three motor variables (body side, body part, cognitive strategy) are coded in the human anterior intraparietal cortex. All tested movements were encoded, arguing against strict anatomical segregation of effectors. Single units coded for diverse conjunctions of variables, with different dimensions anatomically overlapping. Consistent with recent studies, neurons encoding body parts exhibited mixed selectivity. This mixed selectivity resulted in largely orthogonal coding of body parts, which "functionally segregate" the effector responses despite the high degree of anatomical overlap. Body side and strategy were not coded in a mixed manner as effector determined their organization. Mixed coding of some variables over others, what we term "partially mixed coding," argues that the type of functional encoding depends on the compared dimensions. This structure is advantageous for neuroprosthetics, allowing a single array to decode movements of a large extent of the body.
机译:为了澄清后部皮质中的电动机表示组织,我们测试三个电动机变量(身体侧,身体部位,认知策略)如何编码在人类前脑内皮质中。所有测试的运动都被编码,争论严格的效果分离。编码的单个单位,用于各种变量的变量,具有不同尺寸的尺寸剖析。与最近的研究一致,编码身体部位的神经元表现出混合选择性。这种混合的选择性导致车身部件的大正交编码,尽管高度的解剖重叠程度,但是功能性地隔离“效应响应。身体侧和策略未以混合的方式编码,因为效应结果确定其组织。将一些变量的混合编码在其他变量中,我们术语“部分混合编码”是什么,所以功能编码的类型取决于比​​较的尺寸。该结构对于神经调节剂是有利的,允许单个阵列在很大程度上解码体的移动。

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  • 来源
    《Neuron》 |2017年第3期|共16页
  • 作者单位

    CALTECH Div Biol &

    Biol Engn Pasadena CA 91125 USA;

    CALTECH Div Biol &

    Biol Engn Pasadena CA 91125 USA;

    CALTECH Div Biol &

    Biol Engn Pasadena CA 91125 USA;

    Casa Colina Hosp &

    Ctr Healthcare Pomona CA 91767 USA;

    Casa Colina Hosp &

    Ctr Healthcare Pomona CA 91767 USA;

    Univ Calif Los Angeles David Geffen Sch Med Interdept Program Neurosci Dept Neurosurg Los;

    CALTECH Div Biol &

    Biol Engn Pasadena CA 91125 USA;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 神经病学;
  • 关键词

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