...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Neuron >The Mouse Cortical Connectome, Characterized by an Ultra-Dense Cortical Graph, Maintains Specificity by Distinct Connectivity Profiles
【24h】

The Mouse Cortical Connectome, Characterized by an Ultra-Dense Cortical Graph, Maintains Specificity by Distinct Connectivity Profiles

机译：鼠标皮质连接，其特征在于超密集的皮质图，通过不同的连接配置文件保持特异性

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The inter-areal wiring pattern of the mouse cerebral cortex was analyzed in relation to a refined parcellation of cortical areas. Twenty-seven retrograde tracer injections were made in 19 areas of a 47-area parcellation of the mouse neocortex. Flat mounts of the cortex and multiple histological markers enabled detailed counts of labeled neurons in individual areas. The observed log-normal distribution of connection weights to each cortical area spans 5 orders of magnitude and reveals a distinct connectivity profile for each area, analogous to that observed in macaques. The cortical network has a density of 97%, considerably higher than the 66% density reported in macaques. A weighted graph analysis reveals a similar global efficiency but weaker spatial clustering compared with that reported in macaques. The consistency, precision of the connectivity profile, density, and weighted graph analysis of the present data differ significantly from those obtained in earlier studies in the mouse.
机译：分析了小鼠脑皮质的间接布线图案与皮质区域的精制局部分析。在47个区域局部局部的19个区域进行了二十七个逆行示踪喷射器。皮质的平面支架和多种组织学标志物使个人区域的标记神经元的详细计数能够。观察到每个皮质区域的连接权重的对数正态分布跨越5个级，并显示每个区域的不同连接曲线，类似于在MAKQUES中观察到的各个区域。皮质网络的密度为97％，显着高于猕猴报道的66％密度。加权图分析揭示了类似的全球效率，但与猕猴报告的空间聚类较弱。当前数据的连接型材，密度和加权图分析的一致性，精度和加权图分析显着不同于鼠标中早期研究中获得的那些。

著录项

  • 来源
    《Neuron》 |2018年第3期|共28页
  • 作者

    Gamanut Razvan; Kennedy Henry; Toroczkai Zoltan; Ercsey-Ravasz Maria; Van Essen David C.; Knoblauch Kenneth; Burkhalter Andreas;

  • 作者单位

    Univ Claude Bernard Lyon 1 INSERM Stem Cell &

    Brain Res Inst U1208 F-69500 Bron France;

    Univ Claude Bernard Lyon 1 INSERM Stem Cell &

    Brain Res Inst U1208 F-69500 Bron France;

    Univ Notre Dame Interdisciplinary Ctr Network Sci &

    Applicat Dept Phys Notre Dame IN 46556 USA;

    Babes Bolyai Univ Fac Phys Cluj Napoca 400084 Romania;

    Washington Univ Dept Neurosci Sch Med St Louis MO 63110 USA;

    Univ Claude Bernard Lyon 1 INSERM Stem Cell &

    Brain Res Inst U1208 F-69500 Bron France;

    Washington Univ Dept Neurosci Sch Med St Louis MO 63110 USA;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 神经病学;
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号