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首页> 外文期刊>Neuroreport >Diffusion-weighted imaging volume and diffusion-weighted imaging volume growth in acute stroke: associations with fluid-attenuated inversion recovery hyperintensities-diffusion-weighted imaging mismatch and functional outcome
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Diffusion-weighted imaging volume and diffusion-weighted imaging volume growth in acute stroke: associations with fluid-attenuated inversion recovery hyperintensities-diffusion-weighted imaging mismatch and functional outcome

机译：急性中风中扩散加权成像体积和扩散加权成像体积生长：具有流体减毒反转恢复的关联性显着 - 扩散加权成像失配和功能结果

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摘要

Purpose This study assessed the association between diffusion-weighted imaging (DWI) volume and fluid-attenuated inversion recovery vascular hyperintensity (FVH)-DWI mismatch, functional outcome in patients with acute stroke patients receiving endovascular therapy, as well as the value of DWI volume in predicting functional outcome with stroke patients. Methods In 38 stroke patients who received endovascular therapy, FVH-DWI mismatch, DWI volume on admission, DWI volume on follow-up, DWI volume growth, the functional outcome at 3 months [modified Rankin scale (mRS)], and other clinical data were collected. Statistical analysis was performed to compare the associations with the above variables and predict functional outcome after stroke. Results Compared with no FVH-DWI mismatch group (n = 15), FVH-DWI mismatch group (n = 23) had a smaller DWI volume on admission (t = -2.980; P = 0.008), smaller DWI volume on follow-up (t = -2.911; P = 0.009), lower DWI volume growth (t = -2.328; P = 0.031). The 3-month outcome (1.87 +/- 0.92) in patients with FVH-DWI mismatch was better than that (2.93 +/- 1.62) of patients with no FVH-DWI mismatch (t = -2.307; P = 0.032). Spearman's rank correlation analysis revealed that FVH-DWI mismatch (r = 0.327; P = 0.045), DWI volume on admission (r = 0.414; P = 0.010), DWI volume on follow-up (r = 0.486; P = 0.002), and DWI volume growth (r = 0.467; P = 0.003) were positively correlated with mRS at 3 months. ROC analysis showed when the optimal cutoff value of DWI volume on admission was 33.50, the sensitivity and specificity for predicting functional outcome was 60 and 95.65%, respectively. Conclusions Evaluating DWI volume on admission, DWI volume on follow-up as well as DWI volume growth comprehensively may be useful in predicting the functional outcome of acute stroke patients after thrombectomy.
机译：目的本研究评估了扩散加权成像（DWI）体积和流体减毒反转恢复血管超高度（FVH）-DWI错配，急性中风患者接受血管内患者的患者功能结果，以及DWI体积的价值在预测卒中患者的功能结果时。方法在38例中风患者接受血管内疗法，FVH-DWI失配，DWI体积的入学，DWI体积在随访中，DWI体积增长，3个月的功能结果[改进的Rankin规模（MRS）]，以及其他临床数据被收集。进行统计分析以将关联与上述变量进行比较并预测中风后的功能结果。结果与没有FVH-DWI失配基团（n = 15）相比，FVH-DWI失配基团（n = 23）在入场时具有较小的DWI体积（T = -2.980; p = 0.008），后续行动较小的DWI体积（t = -2.911; p = 0.009），降低DWI体积生长（t = -2.328; p = 0.031）。 FVH-DWI失配患者的3个月结果（1.87 +/- 0.92）优于没有FVH-DWI失配的患者（T = -2.307; P = 0.032）。 Spearman的等级相关性分析显示，FVH-DWI失配（R = 0.327; P = 0.045），入院的DWI体积（r = 0.414; p = 0.010），后续DWI体积（r = 0.486; p = 0.002），和DWI体积生长（r = 0.467; p = 0.003）与3个月的MRS呈正相关。 ROC分析显示，当DWI储存时的最佳截止值为33.50时，预测功能结果的敏感性和特异性分别为60％和95.65％。结论评价DWI体积在入院时，DWI体积在随访中以及DWI体积生长综合可用于预测血液切除术后急性中风患者的功能结果。

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  • 来源
    《Neuroreport》 |2019年第13期|共7页
  • 作者

    Zhou Shi-Bo; Zhang Xiu-Ming; Gao Yang; Yang Bo; Shen Wen-Rong;

  • 作者单位

    Nanjing Med Univ Jiangsu Canc Hosp Jiangsu Inst Canc Res Dept Radiol Affiliated Canc Hosp 42;

    Nanjing Med Univ Jiangsu Canc Hosp Jiangsu Inst Canc Res Dept Radiol Affiliated Canc Hosp 42;

    Nanjing Med Univ Jiangsu Canc Hosp Jiangsu Inst Canc Res Dept Radiol Affiliated Canc Hosp 42;

    Nanjing Med Univ Jiangsu Canc Hosp Jiangsu Inst Canc Res Dept Radiol Affiliated Canc Hosp 42;

    Nanjing Med Univ Jiangsu Canc Hosp Jiangsu Inst Canc Res Dept Radiol Affiliated Canc Hosp 42;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 神经病学与精神病学;
  • 关键词

    diffusion-weighted imaging; MRI; prognosis; stroke;

    机译：扩散加权成像;MRI;预后;中风;

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