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Contested futures: envisioning 'Personalized,' 'Stratified,' and 'Precision' medicine

机译:有争议的期货:设想“个性化”,“分层”和“精密”医学

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摘要

In recent years, discourses around "personalized," "stratified," and "precision" medicine have proliferated. These concepts broadly refer to the translational potential carried by new data-intensive biomedical research modes. Each describes expectations about the future of medicine and healthcare that data-intensive innovation promises to bring forth. The definitions and uses of the concepts are, however, plural, contested and characterized by diverse ideas about the kinds of futures that are desired and desirable. In this paper, we unpack key disputes around the "personalized," "stratified," and "precision" terms, and map the epistemic, political and economic contexts that structure them as well as the different roles attributed to patients and citizens in competing future imaginaries. We show the ethical and value baggage embedded within the promises that are manufactured through terminological choices and argue that the context and future-oriented nature of these choices helps to understanding how data-intensive biomedical innovations are made socially meaningful.
机译:近年来,围绕“个性化”,“分层”和“精密”药物的话语已经增殖。这些概念广泛地指的是新数据密集型生物医学研究模式携带的翻译潜力。每个人都描述了对医学和医疗保健的未来的预期,即数据密集型创新承诺带来的。然而,这些概念的定义和用途是多种,有争议的,并以各种各样的想法对所需和所需的期货的各种想法。在本文中,我们解开了“个性化”,“分层”和“精确”术语周围的关键争议,并将认识到的认识,政治和经济背景映射结构以及患者和公民在竞争未来的不同角色富翁。我们展示了通过术语选择制造的承诺的道德和价值行李,并争辩说这些选择的上下文和面向未来的性质有助于了解数据密集型生物医学创新如何在社会上有意义。

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