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首页> 外文期刊>Nutrition and Cancer: An International Journal >Impact of Early Enteral Nutrition on Nutritional and Immunological Outcomes of Gastric Cancer Patients Undergoing Gastrostomy: A Systematic Review and Meta-Analysis
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Impact of Early Enteral Nutrition on Nutritional and Immunological Outcomes of Gastric Cancer Patients Undergoing Gastrostomy: A Systematic Review and Meta-Analysis

机译：早期肠内营养对胃癌患者营养和免疫结果的影响：系统评价和荟萃分析

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ObjecTives: i ne present systematic review ana meta-anaiysis stuay evaluated tne impact ot early enteral nutrition (EN) on postoperative nutritional and immunological outcomes of gastric cancer (GC) patients. Method: The databases of PubMed, Embase, Springer, and Cochrane library were searched till September 2016 to identify studies which evaluated the effects of EN compared with parenteral nutrition (PN) on postoperative immunological and nutritional status and hospitalization time in GC patients. Mean difference (MD) or standard mean difference (SMD) was calculated and I-square statistic test was used for heterogeneity analysis. Results; The present systematic review and meta-analysis have consisted of seven trials, containing 835 GC patients. According to the result of meta-analysis, compared with PN, EN significantly resulted in more increase in the level of albumin [MD = 2.07 (0.49, 3.64)], prealbumin [MD = 9.41 (049, 33.55)], weight [MD = 1.52 (0.32, 2.72)], CD3+ [SMD = 1.96 (1.50, 2.43)], CD4+ [SMD = 2.45 (1.97, 2.93)], natural killers [MD = 5.80 (3.75, 7.85)], and also a decrease in the hospitalization time [MD=-2.39 (2.74, 2.03)]. Conclusion: The results demonstrated that early administration of EN is more effective in improving postsurgical nutrition status and immune index in GC patients. So, based on these results, postoperative early administration of EN is recommended for GC patients where possible.
机译：目的：I NE目前系统评价ANA Meta-Anaiysis Stuay评估TNE影响OT早期肠内营养（EN）胃癌（GC）患者的术后营养和免疫结果。方法：在2016年9月期间搜查了PubMed，Embase，Springer和Cochrane图书馆的数据库，以确定与GC患者术后免疫和营养状况和住院时间的肠外营养（PN）进行评估的研究。计算平均差异（MD）或标准平均差（SMD），并且I-Square统计测试用于异质性分析。结果;目前的系统评价和荟萃分析组成于七项试验，含有835名GC患者。根据Meta分析的结果，与Pn相比，白蛋白水平升高的Zh显着导致较高的（0.49,3.64），prealbumin [MD = 9.41（049,33.55）]，重量[MD = 1.52（0.32,2.72）]，CD3 + [SMD = 1.96（1.50,2.43）]，CD4 + [SMD = 2.45（1.97,2.93）]，天然杀伤者[MD = 5.80（3.75,7.85）]，也减少在住院时间[MD = -2.39（2.74,2.03）]。结论：结果表明，早期介绍ZH在GC患者中改善后勤营养状况和免疫指数方面更有效。因此，基于这些结果，在可能的情况下建议术后早期施用ZH。

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