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首页> 外文期刊>Nutrition Research >Vegetables and lean proteins-based and processed meats and refined grains -based dietary patterns in early childhood are associated with pubertal timing in a sex-specific manner: a prospective study of children from Mexico City
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Vegetables and lean proteins-based and processed meats and refined grains -based dietary patterns in early childhood are associated with pubertal timing in a sex-specific manner: a prospective study of children from Mexico City

机译：基于蔬菜和精益蛋白的和加工肉类和加工的肉类和精致的粮食在幼儿期的饮食模式与性别特异性的呕吐时间相关：对来自墨西哥城的儿童进行预期研究

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Childhood diet has been implicated in timing of sexual maturation. A key limitation of published studies is the focus on individual foods rather than patterns. We hypothesized that dietary patterns characterized by fruits and vegetables during early childhood (age 3 years) would be associated with delayed pubertal timing, whereas energy-dense and meat based dietary patterns would relate to earlier puberty. The study population included 496 participants of a Mexico City birth cohort. The exposures of interest were dietary patterns derived from principal component analysis of dietary data collected via a semiquantitative food frequency questionnaire when the children were 3 years of age, and the outcomes were physician-assessed Tanner stages for pubic hair, breast (girls), genitalia, and testicular volume (boys) between 9 and 18 years, and initiation of menarche (girls). In regression analyses, we estimated adjusted hazard ratios and 95% confidence intervals for having reached Tanner stage &= 4 or initiation of menarche in girls and testicular volume &= 15 mL in boys. Among girls, those in the highest vs lowest textile of vegetables and lean proteins pattern had a 35% (95% confidence interval 3%-67%) lower adjusted probability of having reached breast stage &= 4. Among boys, the processed meats and refined grain pattern score was associated with more advanced testicular development (adjusted hazard ratio = 3.58 [0.62-6.53]). Early childhood dietary patterns may play a role in the tempo of sexual maturation, which could ultimately carry implications for chronic disease susceptibility. (C) 2018 Elsevier Inc. All rights reserved.
机译：童年饮食已经涉及性成熟的时间。发表研究的一个关键限制是关注个别食物而不是模式。我们假设幼儿期（3年龄3年龄）的饮食模式将与延迟青春期时机有关，而能量密集和基于肉类饮食模式将与早期的青春期有关。研究人口包括墨西哥城市出生队列的496名参与者。感兴趣的曝光是饮食模式，当儿童3岁时通过半定量食物频率调查问卷收集的膳食数据的主要成分分析，结果是医生评估的阴毛，乳房（女孩），生殖器和9至18岁之间的睾丸量（男孩），并启动月经初潮（女孩）。在回归分析中，我们估计调整后的危险比和达到坦纳阶段的95％的置信区间; = 4或在女孩和睾丸体积＆amp中的初潮; GT; = 15毫升。在女孩中，与蔬菜和瘦蛋白模式最低的纺织品中最低的那些具有35％（95％置信区间3％-67％）达到乳房阶段的调节概率较低; GT; = 4.在男孩们之间，加工的肉类和精制谷物图案评分与更先进的睾丸发育有关（调整后危险比= 3.58 [0.62-6.53]）。儿童早期饮食模式可能在性成熟的节奏中发挥作用，最终可能对慢性疾病易感性进行影响。 （c）2018年Elsevier Inc.保留所有权利。

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