Who will benefit most from hydrogel rectum spacer implantation in prostate cancer radiotherapy? A model-based approach for patient selection

Vanneste Ben G. L.; Hoffmann Aswin L.; van Lin Emile N.; Van de Voorde Lien; Pinkawa Michael; Lambin Philippe

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Who will benefit most from hydrogel rectum spacer implantation in prostate cancer radiotherapy? A model-based approach for patient selection

机译：谁将受益于来自水凝胶直肠间隔植入前列腺癌放射治疗的大多数人？一种基于模型的患者选择方法

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Background and purpose: Previous studies confirmed that implantable rectum spacers (IRS) decreased acute gastro-intestinal (GI) toxicity in a significant percentage of prostate cancer patients undergoing intensity modulated radiation therapy (IMRT). We developed decision rules based on clinical risk factors (CRFs) to select those patients who are expected to benefit most from IRS implantation.

机译：背景和目的：以前的研究证实，可植入直肠间隔物（IRS）在接受强度调节的放射治疗（IMRT）的主要百分比的前列腺癌患者中，降低了急性胃肠（GI）毒性。我们根据临床风险因素（CRF）制定了决策规则，以选择预计从IRS植入中受益的患者。

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来源
《Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology》 |2016年第1期|共6页
作者
Vanneste Ben G. L.; Hoffmann Aswin L.; van Lin Emile N.; Van de Voorde Lien; Pinkawa Michael; Lambin Philippe;
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作者单位

Maastricht Univ Med Ctr Dept Radiat Oncol MAASTRO Clin Maastricht Netherlands;

Maastricht Univ Med Ctr Dept Radiat Oncol MAASTRO Clin Maastricht Netherlands;

Maastricht Univ Med Ctr Dept Radiat Oncol MAASTRO Clin Maastricht Netherlands;

Maastricht Univ Med Ctr Dept Radiat Oncol MAASTRO Clin Maastricht Netherlands;

Univ Hosp RWTH Aachen Dept Radiat Oncol Aachen Germany;

Maastricht Univ Med Ctr Dept Radiat Oncol MAASTRO Clin Maastricht Netherlands;

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原文格式 PDF
正文语种 eng
中图分类肿瘤学;
关键词
Prostate cancer; Radiotherapy; Rectum spacer; Patient selection; Toxicity prediction;

机译：前列腺癌;放射疗法;直肠间隔物;患者选择;毒性预测;

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1. 对局限性前列腺癌患者采用直肠内球囊中度低分割调强放射治疗的长期结局 [J] . Bin S.Teh, Gary D.Lewis, Weiyuan Mai, 癌症（英文版） . 2018,第012期
2. Who will benefit most from hydrogel rectum spacer implantation in prostate cancer radiotherapy? A model-based approach for patient selection [J] . Vanneste Ben G. L., Hoffmann Aswin L., van Lin Emile N., Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology . 2016,第1期

机译：在前列腺癌放射治疗中，谁将从水凝胶直肠垫片植入术中受益最大？基于模型的患者选择方法
3. Development of a virtual spacer to support the decision for the placement of an implantable rectum spacer for prostate cancer radiotherapy: Comparison of dose, toxicity and cost-effectiveness [J] . Yvonka van Wijk, Ben G.L. Vanneste, Sean Walsh, Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology . 2017,第1期

机译：虚拟垫片的开发，以支持植入直肠间隔物进行前列腺癌放射治疗的决定：剂量，毒性和成本效益的比较
4. Polyethylene glycol hydrogel rectal spacer implantation in patients with prostate cancer undergoing combination high-dose-rate brachytherapy and external beam radiotherapy [J] . Yeh Jekwon, Lehrich Brandon, Tran Carolyn, Brachytherapy . 2016,第3期

机译：高剂量率近距离放射治疗与外照射放疗相结合的前列腺癌患者的聚乙二醇水凝胶直肠垫片植入术
5. Evaluation of Volume Change in Rectum and Bladder During Application of Image-Guided Radiotherapy for Prostate Carcinoma [C] . J. A. Luna, J. I. Rojas Latin American Symposium on Nuclear Physics and Applications . 2016

机译：在癌前列腺瘤中施加图像引导放射治疗期间直肠和膀胱体积变化的评价
6. Developing a Presimulation Protocol for Prostate Cancer Patients Undergoing Radiotherapy [D] . ?Wieworka, Jennifer 2021

机译：开发一种预协议前列腺癌患者接受放射治疗
7. Ano-rectal wall dose-surface maps localize the dosimetric benefit of hydrogel rectum spacers in prostate cancer radiotherapy [O] . Ben G.L. Vanneste, Florian Buettner, Michael Pinkawa, 2019

机译：肛门直肠壁剂量-表面图定位水凝胶直肠垫片在前列腺癌放射治疗中的剂量学益处
8. Who will benefit most from hydrogel rectum spacer implantation in prostate cancer radiotherapy? A model-based approach for patient selection [O] . Vanneste, Ben G. L., Hoffmann, Aswin L., van Lin, Emile N., 2016

机译：在前列腺癌放射治疗中，谁将从水凝胶直肠垫片植入术中受益最大？基于模型的患者选择方法

Who will benefit most from hydrogel rectum spacer implantation in prostate cancer radiotherapy? A model-based approach for patient selection

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