First clinical investigation of. a 4D maximum likelihood reconstruction for 4D PET-based treatment verification in ion beam therapy

Gianoli Chiara; De Bernardi Elisabetta; Ricotti Rosalinda; Kurz Christopher; Bauer Julia; Riboldi Marco; Baroni Guido; Debus Juergen; Parodi Katia

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First clinical investigation of. a 4D maximum likelihood reconstruction for 4D PET-based treatment verification in ion beam therapy

机译：第一次临床调查。离子束疗法4D宠物治疗验证的4D最大似然重建

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Background and purpose: In clinical applications of Positron Emission Tomography (PET)-based treatment verification in ion beam therapy (PT-PET), detection and interpretation of inconsistencies between Measured PET and Expected PET are mostly limited by Measured PET noise, due to low count statistics, and by Expected PET bias, especially due to inaccurate washout modelling in off-line implementations. In this work, a recently proposed 4D Maximum Likelihood (ML) reconstruction algorithm which considers Measured PET and Expected PET as two different motion phases of a 4D dataset is assessed on clinical 4D PET-CT datasets acquired after carbon ion therapy.

机译：背景和目的：在正电子发射断层扫描（PET）的临床应用中，基于离子束治疗（PT-PET）的治疗验证，测量PET和预期PET之间不一致的检测和解释主要受测量的PET噪声，由于低电平计数统计，并通过预期的宠物偏置，特别是由于在离线实施中的冲刷建模不准确。在这项工作中，在碳离子疗法获得的临床4D PET-CT数据集上评估将测量的PET和预期宠物视为4D数据集的两个不同运动阶段的最近提出的4D最大可能性（ML）重建算法。

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来源
《Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology》 |2017年第3期|共7页
作者
Gianoli Chiara; De Bernardi Elisabetta; Ricotti Rosalinda; Kurz Christopher; Bauer Julia; Riboldi Marco; Baroni Guido; Debus Juergen; Parodi Katia;
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作者单位

Ludwig Maximilians Univ Munchen Fac Phys Dept Med Phys Munich Germany;

Univ Milano Bicocca Tecnomed Fdn Dept Med &

Surg Milan Italy;

European Inst Oncol Dept Radiat Oncol Milan Italy;

Ludwig Maximilians Univ Munchen Fac Phys Dept Med Phys Munich Germany;

Heidelberg Univ Hosp Heidelberg Ion Beam Therapy Ctr Heidelberg Germany;

Politecn Milan Dipartimento Elettron Informaz &

Bioingn Milan Italy;

Politecn Milan Dipartimento Elettron Informaz &

Bioingn Milan Italy;

Heidelberg Univ Hosp Dept Radiat Oncol Heidelberg Germany;

Ludwig Maximilians Univ Munchen Fac Phys Dept Med Phys Munich Germany;

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原文格式 PDF
正文语种 eng
中图分类肿瘤学;
关键词
4D PET imaging; Ion beam therapy; Treatment verification; PT-PET; 4D ML reconstruction;

机译：4D PET成像;离子束治疗;治疗验证;PT-PET;4D ML重建;

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专利

1. First clinical investigation of. a 4D maximum likelihood reconstruction for 4D PET-based treatment verification in ion beam therapy [J] . Gianoli Chiara, De Bernardi Elisabetta, Ricotti Rosalinda, Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology . 2017,第3期

机译：第一次临床调查。离子束疗法4D宠物治疗验证的4D最大似然重建
2. 4D offline PET-based treatment verification in scanned ion beam therapy: a phantom study [J] . Kurz Christopher, Bauer Julia, Unholtz Daniel, Physics in medicine and biology. . 2015,第16期

机译：扫描离子束疗法中基于4D离线PET的治疗验证：一项幻像研究
3. SU‐F‐T‐191: 4D Dose Reconstruction of Intensity Modulated Proton Therapy (IMPT) Based On Breathing Probability Density Function (PDF) From 4D Cone Beam Projection Images: A Study for Lung Treatment [J] . Zhou J, Ding X, Liang J, Medical Physics . 2016,第6期

机译：SU-F-T-191：4D剂量改变强度调制质子疗法（IMPT），基于4D锥形光束投影图像的呼吸概率密度函数（PDF）：肺处理研究
4. Clinical investigations of a 4D ML reconstruction strategy for PET-based treatment verification in ion beam therapy [C] . Chiara Gianoli, Rosalinda Ricotti, Elisabetta De Bernardi, IEEE Nuclear Science Symposium and Medical Imaging Conference . 2014

机译：用于离子束治疗中基于PET的治疗验证的4D ML重建策略的临床研究
5. Development, Validation, and Translation of a Respiratory Motion Model-Based 4DCT Technique for Use as a Clinical Protocol for Radiation Therapy Treatment Planning [D] . O'Connell, Dylan Patrick. 2018

机译：基于呼吸运动模型的4DCT技术的开发，验证和翻译，用作放射疗法治疗计划的临床方案
6. 4D registration and 4D verification of lung tumor position for stereotactic volumetric modulated arc therapy using respiratory-correlated cone-beam CT [O] . Keiichi Nakagawa, Akihiro Haga, Satoshi Kida, 2013

机译：使用呼吸相关锥束CT进行立体定向容积调制弧光治疗的肺肿瘤位置的4D配准和4D验证
7. 4D offline PET-based treatment verification in ion beam therapy [O] . Kurz Christopher 2014

机译：离子束治疗中的4D离线pET治疗验证

First clinical investigation of. a 4D maximum likelihood reconstruction for 4D PET-based treatment verification in ion beam therapy

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