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首页> 外文期刊>Retinal cases & brief reports >Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois;
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Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois;

机译：分钟医学院，米洛瓦芝加哥，梅伍德，伊利诺伊州;

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Purpose: To report a case of IgG4-related ophthalmic disease (IgG4-ROD) which presented as choroidal and orbital lesions. Methods: Case report. Results: A 64-year-old man presented with left eye photopsias and a history of IgG4-related perirenal fibrosis. Fundoscopic examination showed multiple bilateral yellow choroidal lesions, and optical coherence tomography showed multiple choroidal lesions. Magnetic resonance imaging of the orbits showed an enhancing lesion present circumferential to the optic nerve, but greater medially, abutting the posterior surface of the left globe. Workup for infectious, autoimmune, and malignant etiologies was negative, and the patient has responded well to treatment with rituximab. Conclusion: IgG4-related disease is a systemic fibroinflammatory disease, which often presents in another location, as in our patient. In cases of uncertain choroidal and orbital lesions, a thorough workup for other etiologies is indicated, and lymphoma must be ruled out. Steroids are the mainstay of treatment for IgG4-ROD, however, small case series and our patient responded well to rituximab. To our knowledge, this is the first reported case of choroidal and orbital lesions secondary to IgG4-ROD.
机译：目的：报告呈现为脉络膜和眶损伤的IgG4相关眼科疾病（IgG4-棒）的情况。方法：案例报告。结果：一名64岁男子患有左眼屏蔽和IgG4相关脑纤维化的历史。基础术检查显示多边的黄色脉络膜病变，光学相干断层扫描显示出多个脉络膜病变。轨道的磁共振成像显示出圆周向视神经呈周向的增强病变，但是邻近左侧地球的后表面更大。对传染病，自身免疫和恶性病因的余地进行了阴性，患者对利妥昔单抗进行了良好的治疗。结论：IgG4相关疾病是一种全身纤维炎症，其通常在另一个位置呈现在我们的患者中。在脉络膜和轨道病变不确定的情况下，表明了对其他病因的彻底余处，必须排除淋巴瘤。类固醇是IgG4-棒的负处理，然而，小型案例系列和我们的患者对Rituximab的反应很好。据我们所知，这是第一个报告的IgG4-棒中杂交和眶痢的病例。

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