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首页> 外文期刊>Retinal cases & brief reports >VITREOUS TREPONEMAL ANTIBODY AS A SUPPLEMENTARY TEST TO SEROLOGY FOR THE CONFIRMATION OF SYPHILITIC CHORIORETINITIS
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VITREOUS TREPONEMAL ANTIBODY AS A SUPPLEMENTARY TEST TO SEROLOGY FOR THE CONFIRMATION OF SYPHILITIC CHORIORETINITIS

机译：玻璃体纤维抗体作为血清学血管科血清学症的补充试验

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Purpose: To report the novel application of nontreponemal and treponemal antibody to confirm diagnosis of ocular syphilis from vitreous samples. Methods: Two distinct case reports emphasizing the importance of confirmatory vitreous treponemal antibody. Multimodal imaging of patients was also applied. Results: We report two distinct cases with positive serum treponemal antibody but opposing vitreous treponemal antibody results. One case with a positive vitreous test responded well to antisyphilitic treatment. By contrast, a case with a negative vitreous result was changed to serpiginous choroiditis, eventually cured by immunomodulatory treatment. Conclusion: Intraocular fluid analysis of nontreponemal and treponemal antibody may play an important role in ruling out suspected ocular syphilis, in settings without a polymerase chain reaction facility, especially immunocompromised patients who are at risk of multiple infections. Further studies are needed to establish the sensitivity and specificity of nontreponemal and treponemal antibody test on vitreous samples.
机译：目的：报告非遗传和培养型抗体的新建应用，以确认从玻璃体样本的眼梅毒诊断。方法：两种明显的病例报告强调确认玻璃体抗体抗体的重要性。还应用了患者的多峰成像。结果：我们报道了两种不同血清纤维抗体抗体但相反的玻璃体纤维抗体抗体结果。一种阳性玻璃体试验的一种情况，对抗潜治治疗良好。相比之下，具有负玻璃体效果的案例改变为血管性脉络膜炎，最终通过免疫调节治疗治愈。结论：非遗传和纤维抗体的眼内液体分析可能在没有聚合酶链式反应设施的情况下排除疑似眼氏蛋白，特别是免疫抑制患者有多种感染的患者在没有聚合酶链反应设施的情况下发挥重要作用。需要进一步的研究来建立在玻璃体样本上的非克莫纳和培养和培养型抗体试验的敏感性和特异性。

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