首页> 外文期刊>Retinal cases & brief reports >INTERMEDIATE UVEITIS ASSOCIATED WITH PERIODIC FEVER, APHTHOUS STOMATITIS, PHARYNGITIS, AND CERVICAL ADENITIS SYNDROME
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INTERMEDIATE UVEITIS ASSOCIATED WITH PERIODIC FEVER, APHTHOUS STOMATITIS, PHARYNGITIS, AND CERVICAL ADENITIS SYNDROME

机译:与周期性发烧,口腔炎,咽炎和宫颈腺炎综合征相关的中间葡萄膜炎

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Background/Purpose: To report two novel cases of intermediate uveitis associated with Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis syndrome. Methods: Observational case reports and review of the literature. Results: Both patients in this report had an established diagnosis of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis syndrome before the onset of ocular inflammation. Infectious and noninfectious systemic conditions known to be associated with intermediate uveitis were excluded. Intermediate uveitis was confirmed clinically in both patients by the presence of vitritis, snowballs, and peripheral snowbanks in the region of the pars plana. Both cases had a course characterized by recurrent inflammation; in which systemic steroid treatment, and in one case, immunomodulatory therapy was necessary. Conclusion: Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis syndrome is an auto-inflammatory fever disorder in childhood. Although other auto-inflammatory disorders such as, Blau syndrome, Muckle-Wells syndrome, and Behcets disease have been associated with various forms of uveitis, Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis has never been reported to be associated with any type of ocular inflammation. We describe for the first time, two cases of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis syndrome presenting with intermediate uveitis.
机译:背景/目的:报告两种与周期性发烧,口腔炎,咽炎和宫颈腺炎综合征相关的中间葡萄膜炎的新病例。方法:观察病例报告和文献审查。结果:本报告中的两种患者在眼睑发作前均确定诊断周期性发烧,口腔炎,咽炎和宫颈腺炎综合征。已知已知与中间葡萄炎有关的感染性和非排感的全身状况。通过在Pars Plana的区域存在玻璃炎,雪球和外围雪地银行,临床诊所地确认中间葡萄炎。这两种病程都有一种特征的局部炎症;在其中全身类固醇治疗中,在一种情况下,需要免疫调节治疗。结论:定期发烧,口腔炎,咽炎和宫颈腺炎综合征是儿童时期的自动炎症发热障碍。虽然其他自动炎症障碍如Blau综合征,麦克风综合征和Behcets疾病都与各种形式的葡萄膜炎,周期性发烧,口腔炎,咽炎和宫颈腺炎从未涉及任何类型眼炎症。我们首次描述了两种定期发烧,口腔炎,咽炎和宫颈腺炎综合征,呈中间葡萄质炎。

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