...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Reviews in medical microbiology >Detection of prevalent mechanism of extended spectrum beta-lactamases, metallo beta-lactamases, and AmpC beta lactamases-producing Klebsiella pneumoniae in the tertiary care hospital
【24h】

Detection of prevalent mechanism of extended spectrum beta-lactamases, metallo beta-lactamases, and AmpC beta lactamases-producing Klebsiella pneumoniae in the tertiary care hospital

机译：检测延长光谱β-内酰胺酶，金属β-内酰胺酶和AMPCβ内酰胺在第三级护理医院产生肺炎群肺炎的普遍机理

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Increasing trends of resistance to antibiotics because of production of beta-lactamases, such as carbapenamase-mediated resistance and extended spectrum beta-lactamases (ESBL), are the most widespread mechanisms documented in Klebsiella pneumoniae. The objective of this study was to understand the prevalent mechanisms of resistance among the clinical isolates of multidrug-resistant (MDR) K. pneumonia from inpatients of a tertiary care hospital at Baghdad, Iraq. Among the 97 MDR K. pneumoniae isolates, 47.4% (n = 46) isolates showed ESBL production, 38.7% (n = 38) showed metallo beta-lactamase (MBL) production, and 22.7% (n = 22) showed both ESBL and MBLs production. Out of 97 MDR K. pneumoniae, 94.3% were found to be biofilm producers. ESBL production was the predominant mechanism of resistance followed by MBL production. Since very limited therapeutic options are available, increasing resistance mechanisms among these organisms is an 'alarming sign'. Copyright (C) 2017 Wolters Kluwer Health, Inc. All rights reserved.
机译：由于β-内酰胺酶的生产，增加对抗生素的抗性抗性趋势，例如甲萘酰胺酶介导的抗性和扩展光谱β-内酰胺酶（ESBL），是在克雷布氏菌肺炎中记载的最广泛的机制。本研究的目的是了解多药物（MDR）K.肺炎的临床分离株抗性的抗性机制，从伊拉克巴格达的第三级护理医院的住院患者。在97mdr k.肺炎群分离物中，47.4％（n = 46）分离物显示ESBL产量，38.7％（n = 38）显示金属β-内酰胺酶（MBL）产生，22.7％（n = 22）显示ESBL和MBLS生产。在97mdr K.肺炎中，发现94.3％是生物膜生产商。 ESBL生产是抵抗的主要机理，然后是MBL生产。由于可获得非常有限的治疗选择，这些生物中的抗性机制增加是一个“令人担忧的标志”。版权所有（C）2017 Wolters Kluwer Health，Inc。保留所有权利。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号