Tight control of disease activity fails to improve body composition or physical function in rheumatoid arthritis patients

Lemmey Andrew B.; Wilkinson Thomas J.; Clayton Rebecca J.; Sheikh Fazal; Whale John; Jones Hope S. J.; Ahmad Yasmeen A.; Chitale Sarang; Jones Jeremy G.; Maddison Peter J.; OBrien Thomas D.

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Tight control of disease activity fails to improve body composition or physical function in rheumatoid arthritis patients

机译：疾病活动的严格控制未能改善类风湿性关节炎患者的身体成分或物理功能

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Objective. RA typically features rheumatoid cachexia [loss of muscle mass (MM) and excessive total fat mass (TFM), especially trunk FM], which contributes to physical disability. Since rheumatoid cachexia is driven by inflammation, it would be anticipated that the success of tight control of disease activity, such as treat-to-target (T2T), in attenuating inflammation would benefit body composition and physical function. This aim of this cross-sectional study was to assess the impact of T2T on body composition and objectively assessed function in RA patients.

机译：客观的。 RA通常具有类风湿性疾病[肌肉质量（mm）的损失和过量的总脂肪质量（TFM），特别是躯干FM]，这有助于物理残疾。由于类风湿性恶疾病是炎症驱动的，因此预计疾病活动的严密控制的成功，例如治疗靶向（T2T），可使身体成分和物理功能受益。这种横断面研究的这种目的是评估T2T对身体组成的影响，并在RA患者中的客观评估功能。

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来源
《Rheumatology》 |2016年第10期|共10页
作者
Lemmey Andrew B.; Wilkinson Thomas J.; Clayton Rebecca J.; Sheikh Fazal; Whale John; Jones Hope S. J.; Ahmad Yasmeen A.; Chitale Sarang; Jones Jeremy G.; Maddison Peter J.; OBrien Thomas D.;
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作者单位

Bangor Univ Sch Sport Hlth &

Exercise Sci Rehabil Musculoskeletal Disorders Exercise Sci Grp;

Bangor Univ Sch Sport Hlth &

Exercise Sci Rehabil Musculoskeletal Disorders Exercise Sci Grp;

Bangor Univ Sch Sport Hlth &

Exercise Sci Rehabil Musculoskeletal Disorders Exercise Sci Grp;

Bangor Univ Sch Sport Hlth &

Exercise Sci Rehabil Musculoskeletal Disorders Exercise Sci Grp;

Bangor Univ Sch Sport Hlth &

Exercise Sci Rehabil Musculoskeletal Disorders Exercise Sci Grp;

Bangor Univ Sch Sport Hlth &

Exercise Sci Rehabil Musculoskeletal Disorders Exercise Sci Grp;

Bangor Univ Sch Sport Hlth &

Exercise Sci Rehabil Musculoskeletal Disorders Exercise Sci Grp;

Bangor Univ Sch Sport Hlth &

Exercise Sci Rehabil Musculoskeletal Disorders Exercise Sci Grp;

Bangor Univ Sch Sport Hlth &

Exercise Sci Rehabil Musculoskeletal Disorders Exercise Sci Grp;

Bangor Univ Sch Sport Hlth &

Exercise Sci Rehabil Musculoskeletal Disorders Exercise Sci Grp;

Bangor Univ Sch Sport Hlth &

Exercise Sci Rehabil Musculoskeletal Disorders Exercise Sci Grp;

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原文格式 PDF
正文语种 eng
中图分类免疫性疾病;
关键词
rheumatoid arthritis; treat-to-target; rheumatoid cachexia; body composition; physical function;

机译：类风湿性关节炎;治疗目标;类风湿性恶棍;身体成分;物理功能;

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专利

1. Tight control of disease activity fails to improve body composition or physical function in rheumatoid arthritis patients [J] . Lemmey Andrew B., Wilkinson Thomas J., Clayton Rebecca J., Rheumatology . 2016,第10期

机译：严格控制疾病活动不能改善类风湿关节炎患者的身体组成或身体功能
2. Can Creatine Supplementation Improve Body Composition and Objective Physical Function in Rheumatoid Arthritis Patients? A Randomized Controlled Trial [J] . Wilkinson Thomas J., Lemmey Andrew B., Jones Jeremy G., Arthritis care & research . 2016,第6期

机译：补充肌酸能否改善类风湿关节炎患者的身体成分和客观身体机能？随机对照试验
3. Early combination disease-modifying antirheumatic drug therapy and tight disease control improve long-term radiologic outcome in patients with early rheumatoid arthritis: the 11-year results of the Finnish Rheumatoid Arthritis Combination Therapy trial. [J] . Rantalaiho V, Korpela M, Laasonen L, Arthritis research & therapy. . 2010,第3期

机译：早期组合疾病改良抗风湿药治疗和严格的疾病控制改善了早期类风湿关节炎患者的长期放射学结果：芬兰类风湿关节炎联合疗法试验的11年结果。
4. The Relationship between Body Composition and Physical Activity in Patients with Crohn's Disease [C] . Maurizio Marra, Olivia Di Vincenzo, Iolanda Cioffi, International Conference on Sport Sciences Research and Technology Support . 2019

机译：克罗恩病患者身体成分与身体活动的关系
5. Association between disease activity, attitudes toward exercise and exercise in patients with rheumatoid arthritis. [D] . Wu, Mei-Chun. 2006

机译：类风湿关节炎患者的疾病活动性，运动态度与运动之间的关联。
6. Early combination disease-modifying antirheumatic drug therapy and tight disease control improve long-term radiologic outcome in patients with early rheumatoid arthritis: the 11-year results of the Finnish Rheumatoid Arthritis Combination Therapy trial [O] . Vappu Rantalaiho, Markku Korpela, Leena Laasonen, 2010

机译：早期组合疾病抗风湿药物治疗和严格的疾病控制改善了早期类风湿关节炎患者的长期放射学结局：芬兰类风湿关节炎联合疗法试验的11年结果
7. Tight control of disease activity fails to improve body composition or physical function in rheumatoid arthritis patients [O] . Lemmey, AB, Wilkinson, T, Clayton, B, 2016

机译：严格控制疾病活动不能改善类风湿关节炎患者的身体组成或身体功能

Tight control of disease activity fails to improve body composition or physical function in rheumatoid arthritis patients

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