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首页> 外文期刊>BJU international >Role of multiparametric magnetic resonance imaging (MRI) in focal therapy for prostate cancer: A Delphi consensus project
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Role of multiparametric magnetic resonance imaging (MRI) in focal therapy for prostate cancer: A Delphi consensus project

机译：多参数磁共振成像（MRI）在前列腺癌局灶性治疗中的作用：Delphi共识项目

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Objective To define the role of multiparametric MRI (mpMRI) for treatment planning, guidance and follow-up in focal therapy for prostate cancer based on a multidisciplinary Delphi consensus project. Materials and Methods An online consensus process based on a questionnaire was circulated according to the Delphi method. Discussion points were identified by literature research and were sent to the panel via an online questionnaire in three rounds. A face-to-face consensus meeting followed the three rounds of questions that were sent to a 48-participant expert panel consisting of urologists, radiologists and engineers. Participants were presented with the results of the previous rounds. Conclusions formulated from the results of the questionnaire were discussed in the final face-to-face meeting. Results Consensus was reached in 41% of all key items. Patients selected for focal therapy should have biopsy-proven prostate cancer. Biopsies should ideally be performed after mpMRI of the prostate. Standardization of imaging protocols is essential and mpMRIs should be read by an experienced radiologist. In the follow-up after focal therapy, mpMRI should be performed after 6 months, followed by a yearly mpMRI. mpMRI findings should be confirmed by targeted biopsies before re-treatment. No consensus was reached on whether mpMRI could replace transperineal template saturation biopsies to exclude significant lesions outside the target lesion. Conclusions Consensus was reached on a number of areas related to the conduct, interpretation and reporting of mpMRI for use in treatment planning, guidance and follow-up of focal therapy for prostate cancer. Future studies, comparing mpMRI with transperineal saturation mapping biopsies, will confirm the importance of mpMRI for a variety of purposes in focal therapy for prostate cancer.
机译：目的基于多学科的Delphi共识项目，确定多参数MRI（mpMRI）在前列腺癌局灶性治疗规划，指导和随访中的作用。材料和方法根据Delphi方法，分发了基于问卷的在线共识过程。通过文献研究确定了讨论要点，并通过在线问卷将其分三轮发送给小组。经过三轮问题的面对面共识会议被发送到由泌尿科医师，放射科医师和工程师组成的48名专家小组。向参加者介绍了前几轮的结果。在最后一次面对面的会议上讨论了由问卷调查结果得出的结论。结果41％的关键项目达成了共识。选择进行局部治疗的患者应具有经活检证实的前列腺癌。理想地，应该在前列腺mpMRI之后进行活检。成像方案的标准化至关重要，并且有经验的放射科医生应阅读mpMRI。在局灶治疗后的随访中，应在6个月后进行mpMRI，然后每年进行mpMRI。在重新治疗之前，应通过针对性的活检确认mpMRI的发现。关于mpMRI是否可以代替会阴模板饱和活检以排除目标病变以外的重要病变，尚未达成共识。结论在与mpMRI的实施，解释和报告有关的许多领域上已达成共识，以用于前列腺癌局灶性治疗的治疗计划，指导和随访。未来的研究将mpMRI与会阴饱和度定位活检相比较，将证实mpMRI在前列腺癌的局部治疗中具有多种用途。

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