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首页> 外文期刊>Occupational and environmental medicine >Multicohort study of change in job strain, poor mental health and incident cardiometabolic disease
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Multicohort study of change in job strain, poor mental health and incident cardiometabolic disease

机译：多级曲目研究工作应变，心理健康状况不佳和事件心脏病疾病

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Several recent large-scale studies have indicated a prospective association between job strain and coronary heart disease, stroke and diabetes. Job strain is also associated with poorer mental health, a risk factor for cardiometabolic disease. This study investigates the prospective relationships between change in job strain, poor mental health and cardiometabolic disease, and whether poor mental health is a potential mediator of the relationship between job strain and cardiometabolic disease.We used data from five cohort studies from Australia, Finland, Sweden and UK, including 47?757 men and women. Data on job strain across two measurements 1–5 years apart (time 1 (T1)–time 2 (T2)) were used to define increase or decrease in job strain. Poor mental health (symptoms in the top 25% of the distribution of the scales) at T2 was considered a potential mediator in relation to incident cardiometabolic disease, including cardiovascular disease and diabetes, following T2 for a mean of 5–18 years.An increase in job strain was associated with poor mental health (HR 1.56, 95%?CI 1.38 to 1.76), and a decrease in job strain was associated with lower risk in women (HR 0.70, 95%?CI 0.60–0.84). However, no clear association was observed between poor mental health and incident cardiometabolic disease (HR 1.08, 95%?CI 0.96–1.23), nor between increase (HR 1.01, 95%?CI 0.90–1.14) and decrease (HR 1.08, 95%?CI 0.96–1.22) in job strain and cardiometabolic disease.The results did not support that change in job strain is a risk factor for cardiometabolic disease and yielded no support for poor mental health as a mediator.
机译：最近的几项大规模研究表明了作业菌株和冠心病，中风和糖尿病之间的前瞻性关系。工作菌株也与心理健康较差的危险因素有关，心肌植物疾病的危险因素。本研究调查了作业应变，心理健康状况差和心脏素质疾病的变化之间的前瞻性关系，以及贫困心理健康是作业菌株和心脏素质疾病之间关系的潜在调解员。我们在芬兰澳大利亚的五个队列研究中使用了数据，瑞典和英国，包括47个？757名男女。分开的两个测量的作业应变数据（分开1-5岁（时间1（t1） - time 2（t2））来定义作业应变的增加或减少。在T2时，心理健康状况差（尺度分布的前25％的症状）被认为是与事件心肌疾病（包括心血管疾病和糖尿病）相关的潜在调解员，其在T2之后为5-18岁。增加在工作菌株中与心理健康状况不佳（HR 1.56,95％？CI 1.38至1.76）有关，并且作业菌株的减少与较低的女性风险降低（HR 0.70,95％？CI 0.60-0.84）。然而，在糟糕的心理健康和事件心脏病（HR 1.08,95％？CI 0.96-1.23）之间没有观察到明确的关联，也不是增加（HR 1.01,95％？CI 0.90-1.14）和减少（HR 1.08,95 ％？CI 0.96-1.22）在作业应变和心脏素质疾病中。结果不支持作业菌株的变化是心肌植物疾病的危险因素，并且没有对差的心理健康作为调解剂的支持。

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