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首页> 外文期刊>Oncology: International Journal of Cancer Research and Treatment >A Novel Color Fluorescence Navigation System for Intraoperative Transcutaneous Lymphatic Mapping and Resection of Sentinel Lymph Nodes in Breast Cancer: Comparison with the Combination of Gamma Probe Scanning and Visible Dye Methods
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A Novel Color Fluorescence Navigation System for Intraoperative Transcutaneous Lymphatic Mapping and Resection of Sentinel Lymph Nodes in Breast Cancer: Comparison with the Combination of Gamma Probe Scanning and Visible Dye Methods

机译：一种新型色彩荧光导航系统，用于嗜乳腺癌中术中的经皮淋巴图和切除哨淋巴结的切除：与γ探针扫描和可见染料方法的组合比较

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Background: This study evaluated the clinical efficacy of a novel imaging system (HyperEye Medical System [HEMS]; Mizuho Corp., Tokyo, Japan) that uses the near-infrared (NIR) fluorescence of indocyanine green to analyze sentinel lymph node (SLN) biopsies for the staging of breast cancer. Methods: This study enrolled 91 patients with histologically confirmed breast cancer that was clinically node negative with a tumor size Results: The identification rate of SLNs was 100% using HEMS, 97.8% using the RI method, and 95.6% using the blue dye method. Two types of lymphatic pathway (LP) were detected in 39 patients (42.9%) and also clearly identified using HEMS-captured color and NIR fluorescence. The incidence of two or more SLNs was significantly higher in patients with a two-route LP to the axilla group than in those with only one route ( p Conclusions: The HEMS NIR fluorescence color imaging method is a promising potential modality for higher-level identification of SLNs than a standard combination of the RI and blue dye methods.
机译：背景：本研究评估了一种新型成像系统的临床疗效（Hypereye Medical System [Hems]; Mizuho Corp.，Tokyo，Japan），其使用近红外（NIR）荧光的吲哚菁绿荧光分析哨淋淋巴结（SLN）用于乳腺癌分期的活组织检查。方法：本研究注册了91例组织学证实乳腺癌的患者，临床节点是阴性，肿瘤大小结果：使用下摆的SLNS的鉴定率为100％，使用RI方法，使用蓝色染料法，95.6％。在39名患者（42.9％）中检测到两种类型的淋巴途径（LP），也可以使用下摆捕获的颜色和NIR荧光清楚地鉴定。两条途径LP对腋窝组的患者显着提高了两种或更多种SLNS的发病率比只有一条途径的患者（P结果：下摆NIR荧光彩色成像方法是高级识别的有希望的潜在模态SLNS比RI和蓝染料方法的标准组合。

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