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首页> 外文期刊>Ocular oncology and pathology. >Elevated Choroidal Thickness and Central Serous Chorioretinopathy in the Fellow Eyes of Patients with Circumscribed Choroidal Hemangioma
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Elevated Choroidal Thickness and Central Serous Chorioretinopathy in the Fellow Eyes of Patients with Circumscribed Choroidal Hemangioma

机译：脉络膜厚度和中央浆液性胆小因素在患者的外观升高的脉络膜血管瘤

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摘要

Objective: To determine whether increased choroidal thickness (CT) is associated with circumscribed choroidal hemangioma (CCH) and whether patients with CCH are predisposed to central serous chorioretinopathy (CSCR). Methods: We performed a retrospective consecutive observational study of 15 fellow eyes of 15 patients who had CCH. A- and B-scan ultrasonography, fluorescein angiography (FA), and optical coherence tomography (OCT) findings were reviewed to confirm the diagnosis of CCH. Fellow eye CT was measured using enhanced depth imaging OCT. FA, indocyanine green angiography, and OCT images of fellow eyes were reviewed for signs of CSCR. Results: Mean subfoveal CT was significantly greater in the fellow eyes of patients with CCH than in age-matched normal eyes ( p = 0.004). Three of 15 (20.0%) fellow eyes of CCH patients had retinal pigment epithelium disruptions and/or pigment epithelial detachments indicative of previous asymptomatic CSCR. Conclusion: In this pilot study, elevated CT was associated with a risk of developing CCH as well as CSCR in patients of varying ages. Patients diagnosed with CCH should be screened for CSCR in the fellow eye. Further exploration of this association may reveal useful clues about the biology of abnormally elevated choroidal hyperpermeability and its various clinical manifestations.
机译：目的：判断是否增加脉络膜厚度（CT）与外接脉络膜血管瘤（CCH）有关，以及CCH患者是否倾向于中央浆液性胆体胰蛋白病（CSCR）。方法：我们对15名患者的15名患者进行了回顾性的连续观察研究。综述了A-和B扫描超声，荧光素血管造影（FA）和光学相干断层扫描（OCT）调查结果证实CCH的诊断。使用增强深度成像OCT测量同源CT。 FA，吲哚菁绿色血管造影和同胞眼的OCT图像被审查了CSCR的迹象。结果：CCH患者的同伴比年龄匹配的正常眼睛（P = 0.004），平均亚骨膜CT显着更大。 CCH患者的15个（20.0％）的同胞具有视网膜色素上皮破坏和/或颜料上皮脱离，指示先前无症状的CSCR。结论：在该试点研究中，升高的CT与发生CCH以及不同年龄患者的CCH以及CSCR的风险有关。应筛查患有CCH的患者，用于同胞中的CSCR。对该协会的进一步探索可能揭示关于异常升高的脉络膜高透析性的生物学及其各种临床表现的有用线索。

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