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首页> 外文期刊>Ocular oncology and pathology. >Hemodynamic Changes Associated with Mydriatic Eye Drop Administration in Anesthetized Pediatric Patients
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Hemodynamic Changes Associated with Mydriatic Eye Drop Administration in Anesthetized Pediatric Patients

机译：麻醉儿科患者中剖腹滴药相关的血流动力学变化

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Background: Dilating eye drops are routinely used in pediatric retinoblastoma patients during anesthetized ophthalmologic exams. Information on the systemic effects of ocular mydriatics, especially in anesthetized pediatric patients, is limited. Objective: The primary aim of this study was to analyze hemodynamic changes during mydriatic eye drop administration in anesthetized pediatric patients. Methods: A retrospective chart review was performed for pediatric retinoblastoma patients who underwent MRI with anesthesia. Baseline blood pressure (BP) and heart rate (HR) were charted for each patient at induction. HR and mean arterial pressure (MAP) measurements were recorded at 5, 10, 15, 30, and 45 min after eye drop administration. Secondarily, we included data from 15 patients who received dilating eye drops while under sevoflurane general anesthetic. All patients were dilated with phenylephrine 2.5 or 10% (depending on age) and tropicamide 1%. Results: The final analysis included 176 anesthesia encounters. The results demonstrate no statistically significant deviation of more than 20% from baseline for either HR or MAP. Additionally, we did not detect any difference between patients who were anesthetized with propofol versus sevoflurane. Conclusions: We did not observe significant hemodynamic instability with administration of dilating eye drops during propofol anesthesia.
机译：背景：在麻醉眼科考试期间常规用于小儿视网膜母细胞瘤患者的扩张滴眼液。有关眼科治疗剂的全身效应的信息，特别是在麻醉的儿科患者中受到限制。目的：本研究的主要目的是分析麻醉儿科患者中散蜱滴药期间的血流动力学变化。方法：对患有麻醉MRI的儿科视网膜母细胞瘤患者进行了回顾性图表审查。为每位患者进行基线血压（BP）和心率（HR）在诱导时进行图。 HR和平均动脉压（MAP）测量在滴眼剂给药后的5,10,15,30和45分钟内记录。其次，我们包括来自15名患者的数据，在七氟醚一般麻醉下接受肿胀的眼药水。所有患者均用苯妥林2.5或10％（取决于年龄）和Tropicamide1％。结果：最终分析包括176个麻醉遭遇。结果表明，从HR或地图的基线上显示出超过20％的统计学显着偏差。此外，我们没有发现用异丙酚与七氟醚麻醉的患者之间的任何差异。结论：在异丙酚麻醉期间，我们没有观察到扩张眼滴的显着血液动力学不稳定。

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