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Patient-Reported Outcomes and Quality of Life after Treatment for Choroidal Melanoma

机译:患者报告的脉络膜黑色瘤治疗后的结果和生活质量

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Background/Aims: Patients with choroidal melanoma can develop psychological morbidity because of visual disability, pain, facial deformity, and fears of metastatic disease. The aim of this study was to report on the prevalence of symptoms, moods, and well-being after radiotherapy or enucleation for choroidal melanoma and how these outcomes changed over time. Methods: Participants were mailed questionnaires approximately 6 months following treatment, then annually on every anniversary of their treatment. Results: Soon after enucleation, patients experienced visual difficulties because of loss of stereopsis and visual field and were concerned about their appearance and about metastatic disease. After radiotherapy, patients were more concerned about local tumor recurrence and more troubled by diplopia and headache. Over time, visual difficulties diminished after enucleation but increased in patients who had received radiotherapy, with concerns about metastasis, loss of health, and tumor recurrence diminishing in both groups. Anxiety tended to diminish whereas depression increased, especially after enucleation. Emotional well-being improved after both kinds of treatment, whereas functional and physical well-being diminished after enucleation but improved after radiotherapy. Self-reported quality of life diminished equally with both kinds of treatment. Conclusion: The findings of this study should help physicians understand what patients tend to feel after treatment for choroidal melanoma.
机译:背景/目的:脉络膜瘤的患者可以出现由于视觉残疾,疼痛,面部畸形和转移性疾病的恐惧而发展心理发病率。本研究的目的是报告放疗后症状,情绪和幸福感的患病率或对脉络膜瘤的脑瘤以及这些结果随着时间的推移而变化。方法:参与者在治疗后约6个月邮寄调查问卷,然后每年在治疗的每周年内完成。结果:在enucleation之后不久,患者因立体和视野的丧失而经历了视觉困难,并担心它们的外观和转移性疾病。放射治疗后,患者更关注局部肿瘤复发,更令人困扰,通过复视和头痛。随着时间的推移,在接受放射治疗的患者后,视觉困难减少,患有放射治疗的患者,令人担忧的转移,健康丧失和两组肿瘤复发。焦虑趋于减少,而抑郁症增加,特别是在enucleation之后。两种治疗后,情绪良好改善,而在放射治疗后功能和物理良好,但在放射后改善。自我报告的生活质量与两种治疗同样减少。结论:本研究的结果应该有助于医生了解患者在治疗脉络膜黑色素瘤后倾向于感受的内容。

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