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首页> 外文期刊>Obesity surgery >Short- and Mid-term Outcomes of 527 One Anastomosis Gastric Bypass/Mini-Gastric Bypass (OAGB/MGB) Operations: Retrospective Study
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Short- and Mid-term Outcomes of 527 One Anastomosis Gastric Bypass/Mini-Gastric Bypass (OAGB/MGB) Operations: Retrospective Study

机译：527个吻合胃旁路/迷你胃旁路（OAGB / MGB）操作的短期和中期结果：回顾性研究

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BackgroundOne anastomosis gastric bypass/mini-gastric bypass (OAGB/MGB) is considered an alternative option in metabolic and bariatric surgery. The aim of this study was to evaluate the safety, efficacy and postoperative challenges of OAGB/MGB as a new procedure.MethodsWe performed 519 primary MGBs and 8 additional second-stage MGBs during 2014-2018. The data were collected from patients' notes as well as the surgeons' prospective data sheets. Two senior surgeons performed the operations. The ultimate primary measures were assessment of the safety and management of the complications. The secondary outcomes were excess weight loss and resolution of the comorbidities.ResultsThe type 2 diabetes mellitus (T2DM) remission rate was 83% and 70% over 1 and 3years, respectively (HBA1C6.5%). Weight loss was 28-152kg (SD 23.11). Excess weight loss ranged from 41 to 125%. Hypertension resolution was 61%, 58% and 58% in the first, second and third years, respectively. Ninety-nine per cent of sleep apnoea patients improved symptomatically and went off the continuous positive airway pressure (CPAP) machine. Two (0.37%) patients developed diarrhoea, cured by shortening the afferent biliopancreatic limb (BPL). Eight (1.5%) stomal ulcers were reported. Two patients (0.37%) developed deranged liver function, revised by shortening the BPL in one patient and a reversal in the second patient. The mean follow-up was 2.5years. Mortality was zero.ConclusionsThis is the largest UK OAGB/MGB study to date showing safety and acceptable results for metabolic syndrome and obesity problems. OAGB/MGB revisional options are rectifying the morbidity and no mortality.
机译：背景，吻合术胃旁路/微胃旁路（OAGB / MGB）被认为是代谢和畜牧手术的替代选择。本研究的目的是评估OAGB / MGB作为新方法的安全性，疗效和术后挑战。在2014 - 2018年期间，在2014 - 2018年进行了519名初级MGB和8个额外的第二阶段MGB。数据从患者的票据和外科医生的潜在数据表中收集。两个高级外科医生进行了操作。最终的主要措施是评估并发症的安全和管理。二次结果是过量减肥和分辨率的分解。分别为2型糖尿病（T2DM）缓解率分别为83％和70％（HBA1C 6.5％）。减肥为28-152kg（SD 23.11）。超重减肥范围为41至125％。高血压分辨率分别为第一个，第二和第三年的61％，58％和58％。九十九九十九个睡眠呼吸暂停患者症状改善，脱离连续的正气道压力（CPAP）机器。两（0.37％）患者开发了腹泻，通过缩短传入的双偶泛酸肢（BPL）来治愈。报道了八次（1.5％）的牙髓溃疡。两名患者（0.37％）发育的紊乱肝功能，通过缩短一个患者中的BPL和第二患者的逆转来修订。平均随访是2.5年。死亡率为零.Conclusionsthis是迄今为止最大的英国OAGB / MGB研究表明代谢综合征和肥胖问题的安全性和可接受的结果。 OAGB / MGB迁移期权纠正发病率和死亡率。

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