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Lip cancer: Reconsidering the at‐risk patients with pathological assessment

机译:唇癌:重新考虑有病理评估的风险患者

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摘要

Abstract Objectives This study was aimed to overview the treatment protocols of lip cancer and find out a cutoff point of tumor diameter and depth of invasion (DOI) for the survival parameters. Materials and Methods One hundred and ninety‐one patients with lip SCC were studied. Results The average age of the patients was 62?years. Among 191 patients, 82.7% of the patients were men, 96.4% of them had lower lip cancer, and 84% were staged as early (pT 1, pT 2 ). Primary tumor excision with neck dissection was applied to 62.3% of the patients. Lymph node metastases rate was found to be 11%, and recurrence rate was 6.3%. There was statistically significant difference in between the tumor diameters and DOI values of patients with and without metastasis, and recurrence ( p ??0.01, p ??0.05, respectively). Regarding to the lymph node metastasis, the optimal cutoff point was found to be 7.5?mm for DOI and 21.5?mm for tumor diameter. Regarding to the recurrence, the optimal cutoff point was found to be 7.5?mm for DOI and 24.5?mm for tumor diameter. Conclusion T 2 lip cancer patients also seem to be in at‐risk group for metastasis and recurrence. As a conclusion, elective neck dissection and frequent follow‐up are recommended for these early‐stage lip cancer patients.
机译:摘要目的本研究旨在概述唇癌的治疗方案,并找出肿瘤直径的截止点和侵袭侵袭(DOI)的存活参数。研究了材料和方法,研究了一百九十一升唇SCC患者。结果患者的平均年龄为62岁。在191例患者中,82.7%的患者是男性,其中96.4%有唇癌的较低癌症,84%患者早期上演(Pt 1,Pt 2)。用颈部解剖初级肿瘤切除施加至62.3%的患者。淋巴结转移率被发现为11%,复发率为6.3%。肿瘤直径与患者的肿瘤直径和没有转移的患者的统计学差异,复发(P 1 0.01,P 1 0.05)。关于淋巴结转移,发现最佳截止点为DOI和21.5Ωmm为7.5Ωmm。肿瘤直径。关于复发,发现最佳的截止点为DOI和24.5Ωmm为7.5Ωmm。结论T 2唇癌患者似乎也处于转移和复发的风险群体中。作为结论,推荐用于这些早期唇癌患者的选择性颈部解剖和频繁的随访。

著录项

  • 来源
    《Oral diseases》 |2019年第3期|共8页
  • 作者单位

    Department of Otorhinolaryngology Head and Neck SurgeryAnkara A.Y. Oncology Education and Research;

    Department of Otorhinolaryngology Head and Neck SurgeryAnkara A.Y. Oncology Education and Research;

    Department of Plastic and Reconstructive SurgeryAnkara A.Y. Oncology Education and Research;

    Department of Otorhinolaryngology Head and Neck SurgeryAnkara A.Y. Oncology Education and Research;

    Department of Otorhinolaryngology Head and Neck SurgeryAnkara A.Y. Oncology Education and Research;

    Department of Otorhinolaryngology Head and Neck SurgeryAnkara A.Y. Oncology Education and Research;

    Department of PathologyAnkara A.Y. Oncology Education and Research HospitalAnkara Turkey;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 口腔科学;
  • 关键词

    cancer; lip; lymph node metastases; pathology; recurrence;

    机译:癌症;唇;淋巴结转移;病理学;复发;

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