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首页> 外文期刊>Otolaryngology--head and neck surgery: official journal of American Academy of Otolaryngology-Head and Neck Surgery >Five-Year Objective and Subjective Outcomes of Velopharyngeal Surgery for Patients with Obstructive Sleep Apnea
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Five-Year Objective and Subjective Outcomes of Velopharyngeal Surgery for Patients with Obstructive Sleep Apnea

机译：阻塞性睡眠呼吸暂停患者Velopharyngeal手术的五年目标和主观结果

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Objective To assess the long-term effects of velopharyngeal surgery on objective and subjective symptoms in patients with obstructive sleep apnea (OSA). Study Design Prospective cohort study. Setting University medical center. Subjects and Methods Eighty-six patients with OSA underwent velopharyngeal surgery, which consisted of revised uvulopalatopharyngoplasty with uvula preservation, with or without concomitant transpalatal advancement pharyngoplasty. The results from polysomnography and the Epworth Sleep Scale after 6 months and 5 years were compared with baseline. Baseline variables were compared between responders and nonresponders. Results Sixty-three patients were successfully followed up at the end of study. The surgical success rate after 6 months and 5 years was 66.67% (42 of 63) and 60.32% (38 of 63), respectively, with no significant difference (P = .459). The apnea-hypopnea index and Epworth Sleep Scale dramatically decreased from baseline after 6 months and 5 years in responders and nonresponders (P < .001 for all). As compared with nonresponders, the responders exhibited larger tonsil size, higher nocturnal lowest oxygen desaturation, lower CT90 (percentage of time with oxygen saturation <90%), and shorter MH (vertical distance between the lower edge of the mandible and hyoid in the midsagittal plane of computed tomography). Tonsil size and CT90 showed significant predictive value for surgery success (P < .001 for both). Conclusion Velopharyngeal surgery was effective in improving nocturnal respiration and excessive daytime sleepiness in patients with OSA at 6-month and 5-year follow-up. Tonsil size and CT90 could be predictors for surgery responders.
机译：目的评估腭颌骨手术对阻塞性睡眠呼吸暂停（OSA）患者客观和主观症状的长期影响。研究设计预期队列研究。培养大学医疗中心。对象和方法8六个患者OSA接受了腭脉络膜手术，其由具有uvula保存的修正uvulopalatopharygoporationGopporaty，有或没有伴随的转母前进性咽部成形术。与基线进行比较6个月和5年后的PolySomNographic和Epworth Sleep Scale的结果。在响应者和非反应者之间比较基线变量。结果六十三名患者在研究结束时成功跟进。 6个月和5岁后的手术成功率分别为66.67％（42％，共63分），分别为60.32％（38％，共63％），没有显着差异（p = .459）。在响应者和无应答者的6个月和5年后，呼吸暂停症患者和欧盟睡眠规模显着降低了基线（所有人的P <.001）。与非反应者相比，响应者表现出较大的扁桃体尺寸，较高的夜间氧去饱和，降低CT90（氧饱和度的时间百分比<90％），并且越短的MH（下颌骨下颌骨和杂有的垂直距离之间的垂直距离计算断层扫描的平面）。扁桃体尺寸和CT90对手术成功显示出显着的预测值（两者都是P <.001）。结论在6个月和5年随访中，腭核手术在改善OSA患者中改善夜间呼吸和过度的白天嗜睡。扁桃体尺寸和CT90可以是外科响应者的预测因子。

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