• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Seminars in hearing >Diabetes and Auditory-Vestibular Pathology
【24h】

Diabetes and Auditory-Vestibular Pathology

机译：糖尿病和听觉前庭病理学

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The relationship between diabetes mellitus (DM) and the auditory/vestibular system has been investigated for more than a century. Most population-based investigations of hearing loss in persons with diabetes (PWD) have revealed a slow progressive, bilateral, high-frequency sensorineural hearing loss. Despite the growing research literature on the pathophysiology of DM-related hearing loss using various animal models and other human studies, knowledge of specific mechanism of the degenerative changes of the inner ear and/or auditory nerve is far from full elucidation. Recent investigations of the mechanisms underlying the association between hearing loss and DM suggest complex combined contributions of hyperglycemia, oxidative stress resulting in cochlear microangiopathy, and auditory neuropathy. An even lesser understood complication of DM is the effect on the vestibular system. Here we provide an overview of animal and human evidence of pathophysiological changes created by DM and its effects on auditory-vestibular anatomy and function.
机译：糖尿病（DM）与听觉/前庭系统之间的关系已经调查了多世纪以上。大多数基于人口对糖尿病（PWD）的听力损失调查（PWD）揭示了缓慢的进步，双边，高频传感器听力损失。尽管使用各种动物模型和其他人类研究的DM相关听力损失的病理生理学的研究文献越来越多，但内耳和/或听觉神经的退行性变化的特定机制的知识远远不受全面阐明。最近调查听力损失与DM关联的机制提出了复杂的高血糖，氧化胁迫导致耳蜗微疗病的复杂合并贡献，以及听觉神经病变。甚至更小于DM的并发症是对前庭系统的影响。在这里，我们概述了DM产生的病理生理学变化的动物和人体证据及其对听觉前庭解剖和功能的影响。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号