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首页> 外文期刊>Separation and Purification Technology >Improved pillar shape for deterministic lateral displacement separation method to maintain separation efficiency over a long period of time
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Improved pillar shape for deterministic lateral displacement separation method to maintain separation efficiency over a long period of time

机译：改进的柱形，用于确定性横向位移分离方法，在很长一段时间内保持分离效率

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Deterministic lateral displacement (DLD) separation utilizes streamlines produced by an array of pillars, which determine the critical diameter. However, particle clogging often occurs at the gaps between the pillars and alters the streamlines. This leads to a drastic reduction in the separation efficiency. In this study, a topology optimization technique has been applied to design a new pillar shape. This will allow the gap between the pillars to be increased in order to minimize particle clogging without affecting the originally designed critical diameter, thereby maintaining higher separation efficiency over a long period. Experimental investigations revealed that a DLD device with the optimized pillar forms a smaller clogging region over a longer period of time than DLD devices with circular- or triangular-shaped pillars. In the DLD device with the optimized pillars enables to maintain 92.2% separation efficiency in displacement mode over 30 min, whereas in circular pillars the separation efficiency in displacement mode progressively reduces to 77%. This result leads to the conclusion that the microfluidic device with the optimized pillar shape can provide consistent separation efficiency for a long period of time. It is believed that this device could be used for separating rigid particles as alternative way to produce super-monodispersed micro-particles with affordable cost. (C) 2016 Elsevier B.V. All rights reserved.
机译：确定性横向位移（DLD）分离利用由柱阵列产生的流线，该柱子确定临界直径。然而，颗粒堵塞通常发生在柱之间的间隙中，并改变流线。这导致分离效率的急剧降低。在这项研究中，拓扑优化技术已经应用于设计新的支柱形状。这将允许柱之间的间隙增加，以便最小化颗粒堵塞而不影响最初设计的临界直径，从而在长时间内保持更高的分离效率。实验研究表明，具有优化支柱的DLD装置在比具有圆形或三角形支柱的DLD器件的时间较长的时间内形成较长的堵塞区域。在具有优化柱的DLD器件中，能够在30分钟内保持位移模式下的分离效率92.2％，而圆柱的位移模式下的分离效率逐渐降低到77％。该结果导致结论是，具有优化柱形的微流体装置可以长时间提供一致的分离效率。据信，该装置可用于将刚性颗粒分离成具有实惠的成本生产超级单分散的微颗粒的替代方法。 （c）2016年Elsevier B.v.保留所有权利。

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