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首页> 外文期刊>Seminars in perinatology >A critical question for NEC researchers: Can we create a consensus definition of NEC that facilitates research progress?
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A critical question for NEC researchers: Can we create a consensus definition of NEC that facilitates research progress?

机译：对NEC研究人员的关键问题：我们可以创建一个促进研究进展的NEC的共识定义吗？

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In the last decades the reported incidence of preterm necrotizing enterocolitis (NEC) has been declining in large part due to implementing comprehensive NEC prevention initiatives, including breast milk feeding, standardized feeding protocols, transfusion guidelines, and antibiotic stewardship and improving the rigor with which non-NEC cases are excluded from NEC data. However, after more than 60 years of NEC research in animal models, the promise of a "magic bullet" to prevent NEC has yet to materialize. There are also serious issues involving clinical NEC research. There is a lack of a common, comprehensive definition of NEC. National datasets have their own unique definition and staging definitions. Even within academia, randomized trials and single center studies have widely disparate definitions. This makes NEC metadata of very limited value. The world of neonatology needs a comprehensive, universal, consensus definition of NEC. It also needs a de-identified, international data warehouse. (C) 2016 Elsevier Inc. All rights reserved.
机译：在过去的几十年中，由于实施了全面的NEC预防措施，包括母乳喂养，标准化的饲养方案，输血准则和抗生素管道和改善非-NEC案例被排除在NEC数据之外。然而，经过60多年的动物模型的NEC研究，“魔法子弹”的承诺来防止NEC尚未实现。还有涉及临床NEC研究的严重问题。缺乏NEC的共同综合定义。国家数据集具有自己独特的定义和分期定义。即使在学术界内，随机试验和单一中心研究也有广泛的定义。这使得NEC元数据值非常有限。新生儿世界的世界需要全面，普遍，共识的NEC定义。它还需要一个可识别的国际数据仓库。 （c）2016年Elsevier Inc.保留所有权利。

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