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首页> 外文期刊>Sexually transmitted diseases >Transgender Women Have Higher Human Papillomavirus Prevalence Than Men Who Have Sex With Men-Two US Cities, 2012-2014
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Transgender Women Have Higher Human Papillomavirus Prevalence Than Men Who Have Sex With Men-Two US Cities, 2012-2014

机译:转型女性患有更高的人乳头瘤病毒患病率,比与男子 - 两个美国城市发生性关系,2012-2014

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Background Human papillomavirus (HPV) prevalence is high among men who have sex with men (MSM), yet little is known about HPV among transgender women (TGW). We assessed HPV prevalence and knowledge among TGW compared with MSM. Methods We enrolled TGW and MSM aged 18 to 26 years from clinics in Chicago and Los Angeles during 2012 to 2014. Participants self-reported gender identity, HIV status, HPV knowledge, and vaccination status. Self-collected anal and oral specimens were tested for HPV DNA (37 types); serum was tested for HPV antibodies (4 vaccine types). Prevalence among unvaccinated TGW and MSM was compared using prevalence ratios (PRs) and 95% confidence intervals (CIs). Participants without DNA or serologic evidence of HPV were considered naive. Results Among 1033 participants, 49 were TGW. Among 44 TGW and 855 MSM who were unvaccinated, any HPV DNA was detected in anal specimens from 39 (88.6%) TGW and 606 (70.9%) MSM (PR, 1.3; 95% CI, 1.1-1.4), and oral specimens from 4 (9.1%) TGW and 81 (9.5%) MSM (PR, 1.0; 95% CI, 0.4-2.5). Antibodies were detected among 37 (84.1%) TGW and 467 (54.6%) MSM (PR, 1.5; 95% CI, 1.3-1.8). Most participants were naive to 1 or more HPV vaccine type/s, including 29 (65.9%) TGW and 775 (90.6%) MSM (PR, 0.7; 95% CI, 0.6-0.9). Most TGW (55.1%) had never heard of HPV vaccine. Conclusions Among TGW, HPV prevalence was high and knowledge was low. Most were still naive to 1 or more HPV vaccine type. Although vaccination ideally occurs prior to exposure, findings support existing national recommendations to vaccinate TGW and MSM, and suggest additional outreach might increase vaccination.
机译:背景技术人乳头瘤病毒(HPV)患病率在与男性(MSM)发生性关系的男性中很高,但在变性女性(TGW)中有很少的人熟知HPV。与MSM相比,我们评估了TGW之间的HPV患病率和知识。方法在2012年至2014年期间,我们从芝加哥和洛杉矶的诊所注册了18至26岁的TGW和MSM。参与者自我报告的性别身份,艾滋病毒状态,HPV知识和疫苗接种状态。测试HPV DNA(37种)的自收集肛门和口腔标本;测试HPV抗体(4种疫苗类型)的血清。使用患病率比(PRS)和95%置信区间(CIS)进行比较未接种的TGW和MSM之间的患病率。没有DNA或HPV血清学证据的参与者被认为是天真的。结果1033名参与者之间,49名是TGW。在44 TGW和855 MSM中,在未接种寄存的855例MSM中,在肛门标本中检测到39(88.6%)TGW和606(70.9%)MSM(PR,1.3; 95%CI,1.1-1.4)和口服标本的肛门标本中检测到任何HPV DNA 4(9.1%)TGW和81(9.5%)MSM(PR,1.0; 95%CI,0.4-2.5)。在37(84.1%)TGW和467(54.6%)MSM中检测抗体(PR,1.5; 95%CI,1.3-1.8)。大多数参与者都是Naive至1或更多HPV疫苗类型/ s,包括29(65.9%)TGW和775(90.6%)MSM(PR,0.7; 95%CI,0.6-0.9)。大多数TGW(55.1%)从未听说过HPV疫苗。结论TGW中,HPV患病率高,知识低。大多数仍然是1或更多HPV疫苗类型。虽然在暴露前理想地发生疫苗接种,但调查结果支持现有的国家建议疫苗和MSM,并建议额外的外展可能会增加疫苗接种。

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