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首页> 外文期刊>ORL: Journal for oto-rhino-laryngology and its borderlands >Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio among Patients with Vestibular Neuritis
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Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio among Patients with Vestibular Neuritis

机译：前庭神经炎患者中性粒细胞对淋巴细胞比和血小板到淋巴细胞比率

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摘要

Objective: To compare the level of the inflammatory markers (IM) neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) among healthy subjects and those presenting with vestibular neuritis (VN). Methods: A cross-sectional retrospective study was conducted in a tertiary hospital setting. The medical records of patients (20-60 years old) who were hospitalized between the years 2005 and 2014 with the diagnosis of VN were retrieved. Inclusion criteria were: (1) acute vertigo lasting for at least 24 h, (2) absence of auditory complaints, (3) presence of horizontal unidirectional nystagmus during physical examination, (4) absence of neurological symptoms or signs. The levels of the IM were compared with levels reported among two large cohorts of healthy subjects, within the same age range. Results: A statistically significant difference was found between the levels of NLR in VN subjects compared with controls, with higher levels of NLR in VN subjects (p < 0.001), while no significant difference was found between both groups concerning the levels of PLR. Conclusion: Higher levels of IM were found among VN patients, with significantly higher levels of NLR, but not PLR. This may suggest a possible inflammatory etiology of VN.
机译：目的：比较健康受试者中炎症标志物（IM）中性粒细胞对淋巴细胞比（NLR）和血小板到淋巴细胞比（PLR）的水平，以及呈前庭神经炎（VN）的那些。方法：在第三级医院环境中进行横截面回顾性研究。检测到2005年至2014年诊断VN的患者（20-60岁）的病人（20-60岁）被检测到VN诊断。纳入标准是：（1）急性眩晕持续至少24小时，（2）缺乏听觉抱怨，（3）体检期间的水平单向眼囊肿，（4）没有神经症状或迹象。在同一年龄范围内比较IM的水平与两个大型健康受试者的群体中报告的水平。结果：与对照相比，VN受试者的NLR水平之间发现统计学上显着差异，VN受试者中较高的NLR水平（P <0.001），而PLR水平的两个组之间没有发现显着差异。结论：在VN患者中发现了更高水平的IM，NLR水平明显高，但不是PLR。这可能表明VN可能的炎症病因。

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