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Epidemiology of the locomotive syndrome: The research on osteoarthritis/osteoporosis against disability study 2005-2015

机译:机车综合征的流行病学:2005 - 2015年骨关节炎/骨质疏松症的研究

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摘要

Although locomotive organ disorders are major causes of disability and require support, little information is available regarding their epidemiology. Prevalence and co-existence of locomotive organ disorders including knee osteoarthritis (KOA), lumbar spondylosis (LS), hip osteoarthritis, and osteoporosis have been determined from baseline results of the Research on Osteoarthritis/Osteoporosis Against Disability (ROAD) study. KOA, LS, and hip osteoarthritis overlap in the population, while KOA and LS co-exist in 42.0% of people. Mutual associations between locomotive organ disorders, metabolic syndrome components, and mild cognitive impairment were found using baseline and 3-year follow-up data from the ROAD study. Logistic regression analysis showed that hypertension, impaired glucose tolerance, and mild cognitive impairment increase the risk of KOA. Osteoporosis at L2-4 was significantly influenced by the presence of femoral neck osteoporosis, and vice versa. In turn, excess weight was inversely associated with the occurrence of femoral neck osteoporosis. Finally, data from the 3rd survey (7-year follow-up) were used to calculate the prevalence of the locomotive syndrome using tests proposed by the Japanese Orthopaedic Association for assessing the risk of developing locomotive syndrome. Subsequently, the age-sex prevalence of stage 1 and stage 2 locomotive syndrome was estimated at 69.8% and 25.1%, respectively.
机译:虽然机车器官障碍是残疾的主要原因,但需要支持,但对其流行病学提供的信息很少。患有膝关节骨关节炎(KOA),腰椎肾炎(LS),髋关节骨关节炎和骨质疏松症,患有骨关节炎/骨质疏松症免受残疾(道路)研究的研究的基线结果确定了患有膝关节骨关节炎(KOA),腰椎胸腺炎和骨质疏松症的患病率和共存。 KOA,LS和HIP骨关节炎在人口中重叠,而KOA和LS共存在42.0%的人中。使用道路研究的基线和3年后续数据,发现了机车器官障碍,代谢综合征组分和轻度认知障碍之间的相互关联。逻辑回归分析表明,高血压,葡萄糖耐量受损,轻度认知障碍增加了KOA的风险。 L2-4的骨质疏松症受股骨颈骨质疏松症存在的显着影响,反之亦然。反过来,过量的重量与股骨颈骨质疏松症的发生成反比相关。最后,第3次调查(7年随访)的数据用于使用日本整形外科协会提出的试验来计算出于发展机车综合征风险的测试的流动性综合征的患病率。随后,阶段1和第2阶段机车综合征的年龄性行为率分别估计为69.8%和25.1%。

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