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Lupus enteritis during pregnancy: A case-based review

机译:怀孕期间狼疮肠炎:基于案例的审查

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摘要

Although the symptoms of systemic lupus erythematosus (SLE) worsen during pregnancy, few previous studies have reported lupus enteritis in pregnant women with SLE. A 29-year-old pregnant Japanese woman presented with acute abdomen. Six years before pain onset, she developed pure red cell aplasia and tested positive for anti-Ro (SS-A) and anti-La (SS-B) antibodies. Anti-DNA antibodies were detected two and a half years later. The patient remained asymptomatic until she developed acute abdomen. A mild increase in anti-DNA antibody levels and a mild decrease in complement levels were observed, and abdominal ultrasound and magnetic resonance imaging revealed the presence of large-volume ascites and edematous thickening of the small intestinal wall. These findings established the diagnosis of lupus enteritis. Her condition improved after treatment with prednisolone 50 mg/day, and she delivered a female infant weighing approximately 1810 g at 37 weeks of gestation. Our study suggests that lupus enteritis should be suspected in female patients with autoimmune disease who develop acute abdomen during pregnancy, and that magnetic resonance imaging is useful in its diagnosis.
机译:虽然在怀孕期间恶化的全身狼疮斑块(SLE)的症状,但以前的少数研究报告患有SLE的孕妇的狼疮肠炎。一名29岁的孕妇日本女性患有急性腹部。在疼痛发作前六年,她开发了纯红细胞增生,并对抗RO(SS-A)和抗-A(SS-B)抗体进行了阳性。在两年半后检测到抗DNA抗体。患者保持无症状,直到她发育急性腹部。观察到抗DNA抗体水平的轻度增加和互补水平的轻度降低,腹部超声和磁共振成像显示出大容量腹水和小肠壁的水性增厚。这些发现建立了狼疮肠炎的诊断。用泼尼松龙50毫克/天治疗后,她的病症改善,她在妊娠37周内递送了重约1810克的女婴。我们的研究表明,狼疮肠炎应怀疑在怀孕期间发生急性腹部的自身免疫疾病的女性患者中,并且磁共振成像在其诊断中有用。

著录项

  • 来源
    《Modern rheumatology》 |2017年第6期|共4页
  • 作者单位

    Natl Ctr Child Hlth &

    Dev Ctr Maternal Fetal Neonatal &

    Reprod Med Dept Obstet Med Setagaya Ku;

    Natl Ctr Child Hlth &

    Dev Ctr Maternal Fetal Neonatal &

    Reprod Med Dept Obstet Med Setagaya Ku;

    Natl Ctr Child Hlth &

    Dev Ctr Maternal Fetal Neonatal &

    Reprod Med Dept Obstet Med Setagaya Ku;

    Natl Ctr Child Hlth &

    Dev Ctr Maternal Fetal Neonatal &

    Reprod Med Dept Obstet Med Setagaya Ku;

    Natl Ctr Child Hlth &

    Dev Ctr Maternal Fetal Neonatal &

    Reprod Med Dept Obstet Med Setagaya Ku;

    Natl Ctr Child Hlth &

    Dev Ctr Maternal Fetal Neonatal &

    Reprod Med Setagaya Ku Tokyo Japan;

    Natl Ctr Child Hlth &

    Dev Ctr Maternal Fetal Neonatal &

    Reprod Med Dept Obstet Med Setagaya Ku;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 免疫性疾病;
  • 关键词

    Lupus erythematosus; Systemic; Pregnancy; Enteritis; Red cell aplasia; Pure;

    机译:狼疮红斑;系统性;妊娠;肠炎;红细胞增生;纯净;

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