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首页> 外文期刊>Supportive care in cancer: official journal of the Multinational Association of Supportive Care in Cancer >Optimizing VAP scars after childhood cancer treatment: a pilot study
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Optimizing VAP scars after childhood cancer treatment: a pilot study

机译：优化儿童癌症治疗后的VAP伤疤：试验研究

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Abstract Purpose Majority of pediatric cancer patients are treated with chemotherapy using Venous Access Ports (VAP). However, after surgical removal of the VAP prominent scars often remain and standard care is lacking. Methods Patients ( N ?=?20) who were willing to participate were included prior to surgical removal of their VAP. All patients were off therapy at time of VAP removal. Patients had the option to either choose from Dermatix?, meridian color therapy (MCT), or no additional treatment (NAT). Assessment of scars was done prior to and 3, 6, and 12?months after surgical VAP removal using Patient and Observer Scar Assessment Scales (POSAS) questionnaires. To identify whether Dermatix? or MCT is associated with better scar healing than without additional treatment, Mann-Whitney U tests were used. Results After 12?months of follow-up, both patients and dermatologists noted VAP scars had healed better after MCT compared to those without treatment ( P ?=?0.010 for both POSAS patient and POSAS observer). No significant differences were observed between VAP scars after Dermatix? use and those with no treatment. Conclusions Scar healing after MCT significantly improved, whereas Dermatix? treatment showed no significant differences compared to NAT. To translate this to daily care, a larger prospective study is needed to validate these findings.
机译：摘要目的，大多数儿科癌症患者使用静脉接入口（VAP）进行化疗。然而，在手术后去除VAP突出的疤痕通常仍然存在，并且缺乏标准护理。方法愿意参加的患者（n？='20）被包括在手术删除他们的VAP之前。所有患者在静止时都会脱离治疗。患者可以选择从Dermatix？，经络颜色疗法（MCT），或没有额外的治疗（NAT）。在使用患者和观察者瘢痕评估尺度（POSAS）问卷的外科VAP去除后，对瘢痕进行评估。确定Dermatix吗？或MCT与更好的疤痕治疗相关，而不是额外的治疗，使用Mann-Whitney U测试。结果12？几个月后的随访，患者和皮肤病学家都注意到，与没有治疗的人相比，VAP疤痕在MCT比较后愈合（P？=？0.010对于POSAS患者和POSAS观察者）。在皮卡汀后VAP疤痕之间没有观察到显着差异？使用和没有治疗的人。结论MCT明显改善后瘢痕愈合，而Dermatix？与NAT相比，治疗没有显着差异。要将其转化为日常护理，需要更大的前瞻性研究来验证这些发现。

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